ABSTRACT Introduction: It has been reported that the main factors behind the emergence of drug resistance is the use and misuse of antimicrobial drugs during the past few decades, but there is also the aspect of epidemic spread of drug-resistant bacteria as a factor. This has caused a major concern with serious implications in human and animal health. It's noted that as much as man's action contribute to the development of antimicrobial drug resistance, it is also seen with domestic animals...
ABSTRACT Ocimum gratissimum and Ocimum suave belong to the family lamiaceae. Folkore medicine claims their use in many conditions. Leaves of 0 gratissimum and 0 suave were extracted in aqueous methanol by maceration, extract was filtered and evaporated using the rotary evaporator and dried to a constant weight in an oven. Phytochemical analysis was carried out to determine the active constituents and Quantification tests were carried out to obtain the amount of phytochmicals in each extract....
ABSTRACT This study was done to evaluate the physicochemical properties, quality control parameters and the dissolution profiles of circulating samples of artemether/lumefantrine sold at Pharmacies in Kampala. The physicochemical parameters and assay of thirteen ( 13) brands of the products were assessed through the evaluation of uniformity of tablet weight, friability test, disintegration test and assay of active pharmaceutical ingredients according to established methods. The dissolution r...
ABSTRACT. The purpose of this study was to evaluate the antibacterial activity, to determine the most efficiency extractive solvents and phytochemical profile of Hot water, Methanol alcohol and Lemon juice extract of Lawsonia inermis (henna) leaf. The plant attracted the attention of researchers because of its use as anti-infective agent. The oily and alcoholic extracts of the plant Lawsonia inermis dried powdered leaves were separately obtained by maceration, while the aqueous was obtained b...
Quality Assurance System Assessment In Bushenyi District Health Facilities
ABSTRACT The Ugandan government has experimented with various supply chain models for delivery of essential drugs and supplies. In 20 I 0, the dual pull-push system was adopted; however drug stock outs are still a common occurrence in health facilities. This study on availability of essential medicines during the dual Pull-Push system in Kaliro District was undertaken; this was to be used as an indirect or direct indicator of availability of essential drugs and medical supplies during the dua...
ABSTRACT The objective of this research was to investigate the anti-hyperglyceamic properties of the aqueous extract green peel of (Banana) musa acuminata 'nakitembe cultivar' in alloxan induced diabetic rats. The extract used was obtaned from the green banana dried and phytochemical analysis and acute toxicity study carried out. Alloxan was used to induce diabetes in experimental albino Rats at a dose of 140mg/kg body weight. After three days, the animals blood sugar levels was tested and t...
ABSTRACT Background Despite the fact that herbal medicines are used by 80% of the World's population (WHO, 2002) and are the main source of health care in the rural communities and the most preferred form of treatment of HIV-related symptoms (Orisatoki and Oguntibeju, 20 I 0), less than I 0% of herbal products in the world market are tru ly standardized to a known active and/or toxic components (Winston et al. , 2007). Study carried out in Western Uganda reported 32.8% of same-day use of he...
ABSTRACT. Irrational prescribing of ARVs to HfV pregnant women is a major problem of poor control of HIV/AIDS all over the world. The researcher assessed the rational prescribing of ARVs and identified factors which contribute to poor prescribing skills and adherence to the National guidelines. A retrospective cross sectional approach was used in studying a sample of pregnant HIV women attending different health institutions in Bushenyi District as from 1st January 2008 to 31 st December 2...
ABSTRACT The history of use of herbal medicine dates back to more than 4000 years. A wide range of plants have been utilized for treatment of multiple disorders of the liver. The utilization has been as extracts of single plants and also compound preparations of more than one-plant type. Herbal medicine has been categorically employed for a variety of medical problems and modern trends have helped in extracting the active ingredients which have been classed into many chemical groups such as a...
Cancer is a group of diseases characterised by uncontrolled proliferation of cells. Of all the types of cancers worldwide, breast cancer is the most commonly diagnosed in women while prostate cancer is the second in men. The current cancer management methods have challenges including unpleasant side effects, high cost and even not effective. As the number of patients is on the rise, physicians look forward with hope to the discovery and development of safe, effective and less toxic anticancer...
ABSTRACT The consequence of political and bloody civil strives in Uganda exposed people to health damaging psychological. physical. chemical. biological and mechanical stressors. with estimated 35% Ugandan suffering from some form or mental disorders. There is dearth of in formation on the impact on the trend evolution and pattern or mental disorders in the two regi ons. This study aims to determine the epidemiology of mental disorders and their patterns of presentation in Eastern and Centra...
ABSTRACT The study on the role of macronutrients on modulation of gut microbiota of Drosophila me/anogaster was carried out in institute of biomedical research laboratory of Kampala international university western campus. The study found that diet and age have influence on gut microbiota. From the findings, the population is recommended to eat well balanced diet.
ABSTRACT. Irrational prescribing of ARVs to HIV pregnant women is a major problem of poor control of HIV/AIDS all over the world. The researcher assessed the rational prescribing of ARVs and identified factors which contribute to poor prescribing skills and adherence to the National guidelines. A retrospective cross sectional approach was used in studying a sample of pregnant HIV women attending different health institutions in Bushenyi District as from 1st January 2008 to 31st December 2009....
ABSTRACT Adverse drug reactions (ADRs) are significant causes of morbidity and mortality and may cause many hospitalizations leading to large economic burdens to patients and to society. Postmarketing surveillance offers assessment of drug released to the market in different categories of people, other than those in whom the drug was tested. However dmg reactions are currently little or not monitored from the open system pharmacy comprising of community pharmacies and drug stores. This study ...