Abstract
Background: Non-tuberculous mycobacteria (NTMs) are ubiquitous, free-living, environmental saprophytic microorganisms. NTMs belong to the genus Mycobacterium which includes Mycobacterium tuberculosis (MTB). NTMs have lately been a major cause of pulmonary disease (PD) in immuno-compromised individuals including HIV-1 patients. NTMs and MTB appear similar based on microscopy, radiology, and clinical symptoms; consequently, this may lead to misdiagnosis. This study sought to establish the prevalence of NTM pulmonary disease in HIV-1 patients presumed to have pulmonary tuberculosis.
Methods: A cross-sectional analytical laboratory study design was used targeting 617 adult HIV-1 infected patients presenting with presumptive pulmonary TB at Bungoma County Hospital Comprehensive Care Clinic in Western Kenya between July 2021 to June 2022.
Results: A total of 75 (12.2%, 4.6 -9.8 CI) of the participants presented with presumptive MTB and had TB-like symptoms while 542 (87.8%, 12.5 -30.7 CI) were negative. Additionally, 56 (9.1%) were infected with NTMs. HIV-positive participants had a significantly higher prevalence of NTMs 62 (11.8%, 5.6 -9.2 CI) compared to 2 (2.1%, 0.4 -1.8 CI). In HI 10 (13.3%) as well as M. kansasii 8 (10.7%). V + study participants P
<div>Wamalwa, < (2024). Prevalence of Non-Tuberculosis Mycobacterium Pulmonary Disease in HIV-1 Patients with Presumptive Pulmonary Tuberculosis in Western Kenya. Afribary. Retrieved from https://track.afribary.com/works/prevalence-of-non-tuberculosis-mycobacterium-pulmonary-disease-in-hiv-1-patients-with-presumptive-pulmonary-tuberculosis-in-western-kenya
<div>Wamalwa, <div>Ochayo "Prevalence of Non-Tuberculosis Mycobacterium Pulmonary Disease in HIV-1 Patients with Presumptive Pulmonary Tuberculosis in Western Kenya" Afribary. Afribary, 04 Jun. 2024, https://track.afribary.com/works/prevalence-of-non-tuberculosis-mycobacterium-pulmonary-disease-in-hiv-1-patients-with-presumptive-pulmonary-tuberculosis-in-western-kenya. Accessed 06 Jul. 2024.
<div>Wamalwa, <div>Ochayo . "Prevalence of Non-Tuberculosis Mycobacterium Pulmonary Disease in HIV-1 Patients with Presumptive Pulmonary Tuberculosis in Western Kenya". Afribary, Afribary, 04 Jun. 2024. Web. 06 Jul. 2024. < https://track.afribary.com/works/prevalence-of-non-tuberculosis-mycobacterium-pulmonary-disease-in-hiv-1-patients-with-presumptive-pulmonary-tuberculosis-in-western-kenya >.
<div>Wamalwa, <div>Ochayo . "Prevalence of Non-Tuberculosis Mycobacterium Pulmonary Disease in HIV-1 Patients with Presumptive Pulmonary Tuberculosis in Western Kenya" Afribary (2024). Accessed July 06, 2024. https://track.afribary.com/works/prevalence-of-non-tuberculosis-mycobacterium-pulmonary-disease-in-hiv-1-patients-with-presumptive-pulmonary-tuberculosis-in-western-kenya