EFFECT OF ISONIAZID ON THE METABOLISM OF PARACETAMOL IN RATS
ABSTRACT The metabolism of Paracetamol has been studied in Isoniazid pretreated albino rats and compared with control. During this study, thirty-five (35) laboratory albino rats were used divided into five (5) groups of seven (7) rats each. Group I served as control and the rats were only administered with 120mg/5ml/kg body weight dose of Paracetamol interperitoneally. However, Groups II-V served as test groups and the members were pretreated with 10mg/kg body weight dose of Isoniazid interpe...