Abstract: Although avertable and treatable, pneumonia is still one of the top five causes of mortality in the developing world especially in Southern Africa. One major challenge being faced globally today in the field of public health is the pneumococcal resistance to antibiotics both in infants and adults. The purpose of this review was to compare rates and causes of treatment failure in South Africa, Zambia, Malawi, and Mozambique. Articles used for this review were searched for in electro...