Beta-lactamase enzymes e.g. metallo β-lactamases (MBLs) that produces Gram-negative bacteria is no doubt one of the widely spread resistance strategies which was geared by these group of bacteria towards β-lactam drugs. MBLs hydrolyzes bacteria and resist carbapenems. This study aimed at determining the antibiogram and the production of MBLs by Klebsiella species from poultry feaces in Owo metropolis. From Poultry feaces aseptically collected Klebsiella species was isolated using MacConkey agar (MAC) as well as Eosin Methylene Blue (EMB) Agar followed by conventionally characterization. Antimicrobial susceptibility test of the isolates were by disc diffusion method against ceftazidime (30μg), cefuroxime (30μg), gentamicin (10 μg), cefixime (5 μg), ofloxacin (5 μg), augmentin (30 μg), nitrofurantoin (300 μg) and ciprofloxacin (5 μg). The isolated Klebsiella species was screened for MBL production by determining their susceptibility to imipenem and this was confirmed using imipenem-EDTA combined disc test for phenotypic detection of MBLs. Klebsiella species isolated showed highest resistance to augmentin (97.9%) and least resistance to nitrofurantoin (18.8%). Out of the 48 Klebsiella species isolated from poultry feaces, 7 (14.6%) produced MBL. The production of MBLs by Klebsiella species in the community portends serious public health concern since these organisms are resistant to the carbapenems. Efficient detection and sustainable intervention protocol to control the emergence and spread of antibiotic resistant bacteria in the community are necessary to contain this dilemma; and there is need for poultry farmers to guide against the legal implications of raising birds with MBLs producing bacteria.
Olugbenga, B (2023). Antibiogram and Detection of Metallo-Beta-Lactamase Producing Klebsiella Species Isolated from Poultry Feaces in Owo Metropolis with its Legal Critics.. Afribary. Retrieved from https://track.afribary.com/works/antibiogram-and-detection-of-metallo-beta-lactamase-producing-klebsiella-species-isolated-from-poultry-feaces-in-owo-metropolis-with-its-legal-critics
Olugbenga, Barr. "Antibiogram and Detection of Metallo-Beta-Lactamase Producing Klebsiella Species Isolated from Poultry Feaces in Owo Metropolis with its Legal Critics." Afribary. Afribary, 17 Dec. 2023, https://track.afribary.com/works/antibiogram-and-detection-of-metallo-beta-lactamase-producing-klebsiella-species-isolated-from-poultry-feaces-in-owo-metropolis-with-its-legal-critics. Accessed 14 Nov. 2024.
Olugbenga, Barr. . "Antibiogram and Detection of Metallo-Beta-Lactamase Producing Klebsiella Species Isolated from Poultry Feaces in Owo Metropolis with its Legal Critics.". Afribary, Afribary, 17 Dec. 2023. Web. 14 Nov. 2024. < https://track.afribary.com/works/antibiogram-and-detection-of-metallo-beta-lactamase-producing-klebsiella-species-isolated-from-poultry-feaces-in-owo-metropolis-with-its-legal-critics >.
Olugbenga, Barr. . "Antibiogram and Detection of Metallo-Beta-Lactamase Producing Klebsiella Species Isolated from Poultry Feaces in Owo Metropolis with its Legal Critics." Afribary (2023). Accessed November 14, 2024. https://track.afribary.com/works/antibiogram-and-detection-of-metallo-beta-lactamase-producing-klebsiella-species-isolated-from-poultry-feaces-in-owo-metropolis-with-its-legal-critics