Assessment of the Quality of Fixed Dose Quinine Sulfate Tablets Sold in Bushenyi Based On the BP Specifications

KANDOLE RICHARD 100 PAGES (18942 WORDS) Pharmacy Project

TABLE OF CONTENTS

DECLARATION ........................................................................................................................................................ 1

APPROVAL .•••.••••••••.•.••••••.••••••..•.•••••..••••••.•••••••.••••••.•.•••.••.•••••.•••••.••••.••.•••••..•..•..•...••.•..•.•••..•.....•..•••.•.•••.•••••.•.••..••••• II

DEDICATION ......................................................................................................................................................... Iii

ACKNOWLEDGEMENT .......................................................................................................................................... IV

LIST OF ABBREVIATIONS AND ACRONYMS ............................................................................................................ V

OPERATIONAL DEFINITION OF TERMS .................................................................................................................. Vi

TABLE OF CONTENTS ............................................................................ ,.. ........................................................... VIIi

ABSTRACT ............................................................................................................................................................. 1

CHAPTER ONE ....................................................................................................................................................... Z

INTRODUCTION ..................................................................................................................................................... 2

1.0 INTRODUCTION .................................................................................................................................................... 2

1.1 8ACKGROUNDTOTHESTUDY .............................................................................................................................. 2

1.2 PROULEM STATEMENT ...................................................................................................................................... 3

1.3 JUSTIFICATION OF THE :lTlJDY .............................................................................................................................. 4

1.4. STUDY OBJECTIVES ............................................................................................................................................. 5

1.4.1. GENERAL OBJECTIVES ..................................................................................................................................... 5

I .4.2. SPECIFIC OBJECTIVES ...................................................................................................................................... 5

1.5 RESEAI

1.6 SCOPE OF THE STUDY ........................................................................................................................................... S

l. 7 CONCEPTUAL FLAME WORK ............................................................................................................................... 6

CHAPTER TWO ..... ~ ................................................................................................................................................. 7

LITERATURE REVIEW ............................................................................................................................................. 7

2.0 INTROOliCTION ................................................................................................................................................. 7

2.! KNOWLED

2.2 A TTJTUDES Of RUH.AL iviOTHERS ABO\JT JMMUNlZA !'!ON •........................... ., .................................................... 8

2.3 PRACTICES OF MOTHERS TOWARDS IMI>oJliNlZATION .......................................................................................... 9

CHAPTER THREE ................................................................................................................................................... 11

METHODOLOGY ................................................................................................................................................... 11

3.0. INTRODUCTION ................................................................................................................................................. 11

3.1. STUDY AREA ..................................................................................................................................................... 11

3.2. STUDY DESIGN .................................................................................................................................................. 11

3.3. STUDY PERIOD ................................................................................................................................................. 12

3.4. STUDY POPULATION ......................................................................................................................................... 12

3.5. SAMPLE SIZE DETERMINATION ........................................................................................................................ 12

3.6. SAMPLE TECJ-INIQIJES ..................................................................................................................................... 13

3.7. SAMPLING STRATEGY ................................................................................................................................. 13

viii

3. 7.1 INCLUSION CRITERIA ................. ................. .. ............... .... ...... . ......................................................... 13

3.7.2 EXCLUSION CRITERIA ..•........•................................•.•............................................................................... 13

3.8. DEFINITION OF VARIABLES ........•..•......•.........................•.•...................••.............•..................•.......................... 13

3.8.1. THE INDEPENDENT VARIABLES ..•.••.....••........•........•......••.•.........•....•••.••............•............•............................... 13

3.8.2. THE DEPENDENT VARIABLES .....•...............•.........•..........................................•....................................•......... 13

3.1 0. DATA COLLECTION .•......•..........•.........•...............•.......•................................................................•.................. 14

3 .II. DATA ANALYSIS AND MANAGEMENT ...............................................................•............................................ 14

3.!2. DATA PRESENTATIONS .............•.........•.•..................•.................................................................•.............•.. 14

3.13 ETHICALCONSIDERATIONS •.........•.•................................•...................................•..•...............................•••....••. 14

3.14 STUDY LIMITATIONS AND REMEDIES ..............••.••................•......•••......•......•.....••.•.......••••.......••.......•..............•. 15

3.15. DISSEMINATION Of RESULTS ••...•............•........•......•.•....•......•..•••.....••.....•..•.•.••.......••.............•..•..................... 15

CHAPTER FOUR .................................................................................................................................................... 16

RESUlTS ............................................................................................................................................................... 16

4.0 INTRODUCTION ................................................................................................................................................. :l6

4.!.0. DEMOGRAPHIC CHARAC ,-cRISTICS ............................................................................................................... 16

4.1. 1: Distribution of respondents according to their demographic chacteristics ............................................ 16

4.1.2 Knowledge of Mother's on Immunization ................................................................................................ 18

4. 1.3 Distribution of mothers according to knowiedge about the definition of immunization ......................... 18

4.2.2 Distribution of mothers according to the source ofkno\vtedge on immunization .................................... 19

4.2.3 Distribution of mothers according to knov..-ledge abotJt wh·.::re rnothers mke their chiidr~n fur

inlJnunization .................................................................................................................................................. 19

4.2.4 Distribution of mothers according to knowledge ofditferent immunizable diseases in children of0-5

years of age. IF65 .............................................................................................................................................. 20

4.2.5 Distribution of mothers according to knowledge about correct earliest age ofimmunization .................. 21

4.2. 6 Distribution of mothers according knowledge on last age for immunization ........................................ 21

4.3. ATflTUDE OF MOTHERS ABOUT IMMUNJZAT!ON ............................................................................. 22

4.3.1: Distribution of mothers according to belief about importance of immunization ..................................... 22

4.3.2: Distribution of mothers according to benefits of immunization n=65 ..................................................... 22

4.3.3: Distribution of mothers according to belief about Safety of vaccines n=65 .......................................... 23

4.3.4: Distribution of mothers according to reasons for vaccines being unsafe ................................................. 23

4.3.5 Distribution of mothers according to days when immunization is done. n=65 ........................................ 24

4.3.6. Distribution of mothers according to convcnie11ce of date and place fbr immunization. n=61 ................ 24

4.4.0. MOTIIER'S PRACTICES ON IM,tlJNI7.ATION .................................................................................................... 25

4.4. 1: Distribution of mothers according to immunization status of children. n=-=65 ......................................... 25

4.4.2: Jrnrnunization practices in relation to distance between different households and immunization centers .

........................................................................................................................................................................... 26

4.4.3: Distribution of mothers according to reasons fbrno immunization/partial immunization. n=i7 ............ 26

3.4.4: Distribution of mothers according to availability of child health card. n=60 ......................................... 28

4.4.5: Distribution mothers according to reasons for no card ............................................................................ 28

4.4.6: Participation of mothers in immunization Jxaclices irt relation to their it~vel ofeducation ...................... 29

4.4.7: Distribution of mothers on how they were handled by vaccination team ................................................ 30

n=60 ................................................................................................................................................................... 30

4.4.8. Distribution of mothers according to charges for immunization services n=60 ....................................... 30

CHAPTER FIVE ...................................................................................................................................................... 31

DISCUSSION OF FINDINGS, CONClUSION •\ND R£COMMEIIIDATION5 .................................................................. 31

ix

5. I DISCUSSION .................................................................................................................................................. 31

5.1.2. Demographic characteristics of respondents .......................................................................................... 31

5.1.3 Knowledge of Mothers about Immunization . .......................................................................................... 31

5.1.4. ATTITUDE OF MOTHERS ON IMMUNIZATION .............................................................................. 32

5.1.4. PRACTICES OF MOTHERS ON IMMUNIZATION ........................................................................ 33

5.2.0 CONCLUSIONS .................................................................................................................................... 35

5.3.0 RECOMMENDATIONS ............................................................................................................................... 35

REFERENCES .......................................................................................................................................................... 36

APPENDICES ........................................................................................................................................................ .40

APPENDIX 1: CONSENT FORM .............................................................................................................................. .40

APPENDIX II: ........................................................................................................................................................ .41

QUESTIONNAIRE ................................................................................................................................................. .41

APPENDIX Ill: ........................................................................................................................................................ 46

INTRODUCTORY LETTER ........................................................................................................................................ 46

APPENfliX IV .......................................................................................................................................................... 47

BUDGET ................................................................................................................................................................ 47

APPENDIX ............................................................................................................................................................ .48

WORK PLAN ......................................................................................................................................................... 48

APPENDIX Vl ........................................................................................................................................... , ............ .49

MAP OF UGANDA ................................................................................................................................................ .49

APPENDIX VII ........................................................................................................................................................ SO

MAP OF KISORO DISTRICT ......................................................................................................................... ., ......... 50

ABSTRACT Immunization involves the process of making children immune or resista.11t to an infectious disease typically by administration of a vaccine. It is one of the most cost effective public health interventions for reducing child mortality and morbidity hence it is the best investment a country can make to ensure a healthy population. Globally it saves about 2-3 million lives annually and provides one of the least expensive tools for preventing childhood vaccine preventable diseases, avoiding costs of curative care. The study was a descriptive cross-sectional study on knowledge attitude and practices of mothers towards immunization of children aged 0-5 years in Mugwata village, Gisozi parish Muramba Sub County, Kisoro district. The general objective was to determine the knowledge. attitude and practices of mothers towards immunization of children of aged 0-5 years. The specific objectives were: to assess knowledge of the rural mothers about immunization, to study the attitudes of rural mothers towards immunization. and to determine the practices of mothers on immunization of children aged 0-5 years. Both quantitative and qualitative methods of data collection were employed. A questionnaire with both closed and open ended questions was used and 65 respondents were sampled. Results: There study observed a high knowledge on immunization, 96.9% of the mothers were able to define immunization approp1iately, 93.8% identified benefits of immunization and at least every mother mentioned one immunizable disease. Poliomyelitis and measles were the most known vaccine preventable disease. However. the study revealed that there was lack of knowledge on the correct earliest age and last age for immunization of children 0-5 years of age. Only 66.2% knew the correct earliest age of immunization and only 21.5% of moth