Determination of Complete Blood Cell Count of Sudanese Pregnant Women at Second Trimester- Omdurman locality

Abstract

This is a case control study , conducted in Omdurman Locality during the period from February to May 2015 , to determine CBC (Hb, RBCs, HCT , MCV , MCH ,MCHC, Plets , WBCs, leukocyte differential count , RDW and MPV) of (80) healthy Sudanese pregnant women at second trimester as case and (40) non pregnant women at matched age in Omdurman locality were used as control in this study . Pregnant women at second trimester were informed about the study and agreed for participatin as cases . A questionnaire was designed to collect information about the study group such as demographic data ,age , number of pregnancies , month of pregnancy ,history of abortion and whether they visit the clinic regularly .

2.5 ml venous blood was collected in EDTA anticoagulant container . automated hematological analyzer (Sysmex KX-21N) was used to measure CBC and the result were analyzed by independent T test of SPSS computer program . This study was concluded that : There was significant decrease in Hb, HCT, RBCs count, lymph % and absolute lymph and PDW in pregnant women when compared with control group (p.< 0.02 ) .and significant increase (p.=0.00) in, TWBCs neut% and absolute neut count in pregnant women when compared with control group. There was no significant difference in MCH, MCHC, Plets count , MCV, RDWcv, and MPV in pregnant women when compared with control group. There was significant decrease in Hb, HCT, RBCs count, MCH (p.< 0.02) and significant increase in TWBCs, Neut% , absolute Neut and MPV (p.=0.00). No significant difference in MCV, MCHC, Lymph % , absolute lymph ,plets count ,PDW and RDW in abortion pregnant women when compared with non abortion pregnant women(p.> 0.08). There was significant decrease in Hb and absolute Neut (p.< 0.04 )and significant increase in lymph % and PDW (p. < 0.03) .also there was no significant difference in HCT, MCV, MCH, MCHC, RDWcv, TWBCs, Neut%, Plets count, MPV,RBCs count in pregnant women >30 years in age when compared with pregnant women 0.06). There was no significant difference in hematological parameter between pregnant women with less than 3 pregnancies and pregnant women with more than 3 pregnancies (p. > 0.10) (the mean of pregnancy 1-6 pregnancies) .