Search result: Ten controlled clinical studies relevant to the topic were found. Clinical outcomes: The results indicate: - GIC/RM-GIC have higher caries-preventive effects than composite/amalgam in cases were no additional fluoride was provided to patients have been shown; - Topical fluoride is indicated as caries-preventive; - Mineral containing supplements, with and without casein appear to be at least as effective as topical fluoride in caries prevention; - The effect of chlorhexidine ge...
Search result: There is still a lack of studies to this topic and only two clinical studies concerning restorations in the primary dentition were found. Clinical outcomes: The results of (conventional) high-viscosity GIC indicate no difference to amalgam while, lowviscosity GIC perform significantly worse than amalgam. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYST...
Search result: Only three clinical studies were found. Clinical outcomes: The results indicate no difference in the longevity between both types of materials. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases�...
Search result: Seven clinical studies to topics concerning orthodontic bonding, root- and tooth restorations were found. Clinical outcomes: The results indicate a higher cariostatic effect of GIC for orthodontic bonding and tooth restorations in permanent teeth. No difference was found for tooth restorations in primary teeth when compared to fluoride containing composite and root restorations. State of evidence and recommendations: The quality of the existing evidence requires further asses...
Search result: One prospective clinical controlled trial was found. Clinical outcomes: The results indicate that coating increases wear resistance. State of evidence and recommendations: More clinical (prospective) randomised control trials (RCT) are needed to confirm the laboratory results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limit...
Search result: There is a lack of clinical studies to this topic: Only three clinical trials were found and traced. Clinical outcomes: The results are conflicting or suggest no difference between conventional GIC and Compomers in regard to their anticariogenic effects. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental ...
Search result: Twelve clinical trials were found and traced. Clinical outcomes: The overall results suggest no difference between RM-GIC and Compomers in regard to their anticariogenic effects. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are...
Search result: One clinical trial was found and traced concerning resin-modified GIC (RM-GIC). The material was Fuji II LC (compared to: Tetric Flow and Helioseal F). No trials were identified comparing conventional GIC (C-GIC) with composite resin. Clinical outcomes: The overall results suggest a higher antibacterial effect for resin-modified GIC (RM-GIC) up to 6 months. State of evidence and recommendations: All evidence from one clinical, controlled trial, only. This is still an emerg...
In 2012, the Systematic Review initiative for Evidence-based Minimum Intervention in Dentistry (SYSTEM) has been accepted as research entity with programme status within the Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa. The aim of the initiative is to establish an applicable evidence-based body of clinical knowledge in the field of Minimum Intervention (MI) dentistry. This article provides a brief overview over SYSTEM’s activities during 2014/15.
The evidence for the efficacy and cost-effectiveness of sealants in reducing occlusal caries in molar teeth has been highlighted in a number of articles in highly rated journals. The most commonly used sealant material is resin composite. Its caries-preventive effect relies on the sealing of pits and fissures through micro-retention, created through tags after enamel acid etching. However, these are easily destroyed by saliva contamination, which reduces micro-retention and consequently, ...
A large percentage of evidence concerning dental interventions is based on laboratory research. The aim of this metaepidemiological study is to establish whether valid clinical inferences and recommendations can be made on basis of the current laboratory evidence concerning high-viscosity glass-ionomer cement (HVGICs) versus amalgam as materials for placing restorations in permanent posterior teeth for daily dental practice. HVGICs may offer a suitable clinical alternative to amalgam for ...
In 2012, the Systematic Review initiative for Evidence-based Minimum Intervention in Dentistry (SYSTEM) has been accepted as research entity with programme status within the Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa. The aim of the initiative is to establish an applicable evidence-based body of clinical knowledge in the field of Minimum Intervention (MI) dentistry. This article provides a brief overview over SYSTEM’s activities during 2013/14.
Background: Inferences based on naïve-indirect comparisons, particularly concerning the effectiveness of different types of tooth restorations, are still relatively common in reviews of the dental literature: Thus, the aim of this study was to illustrate, by use of a simple trial simulation, the potential impact of naïve-indirect comparison on effect estimates. Methods: Clinical trials were simulated by assuming comparisons of two interventions with dichotomous outcomes. The treatment ef...
This protocol has been registered with the International Prospective Register for Systematic Reviews (PROSPERO) on the 10 July 2012 under registration number CRD42013006487 (Available online from http://www.crd.york.ac.uk/prospero/display_record.asp?ID=CRD42013006487). REVIEW QUESTION: Do conventional glass-ionomer restorations, in patients with single and/or multi-surface cavities in posterior permanent teeth, have a higher failure rate than direct composite resin restorations? SYSTEMATIC...
597 articles were reviewed, 426 did not comply with the exclusion criteria and were rejected. 171 articles were accepted as evidence. The results show an emerging evidence base for CAMBRA in support for the viability of assessing the risk factors: Saliva flow; Salivary counts of S. mutans and Lactobacilli; Frequency of fermentable carbohydrate intake; past caries experience and for the use of Dental chewing gum; Chlorhexidine; Topical fluoride; Glass ionomers; CPP/ACP for caries management.