ABSTRACT The effect of Ethylenedianinetetraacetic acid (EDTA) on lead content of blood has not been worked on in vitro. This led to carrying out this research. The aims of this research is to ascertain if EDTA has any effect on blood lead levels if the sample is collected using an EDTA tube and also to find out if there is any significant difference in the blood lead levels of the same sample when collected with an EDTA tube and a non-EDTA tube. Hundred (100) males who are commercial painter...
This study was a descriptive study (case and control) conducted in Khartoum state (Goze Elrimela) during the period from June (2010) —October (2014). This study was aimed to detect the cytological changes of urinary tract cells among Sudanese patients suffering from urinary schistosomiasis.. The secondary data was collected from books and internet. Random samples of 75 urine samples were taken from both male and female at a different agesof patients that effected by urinary schistosom...
This is prospective study to measure CBD, CHD, GB and cystic duct by U/S and MRCP and to test the accuracy of each modality in diagnosing causes of biliary system obstruction. The study was done in Khartoum state hospitals (Ibn sena-Soba on february2018), 52 patients were tested by both U/S and MRCP. Using U/S 3.5MHz prom, TR (1500-200ms), TI (110-150ms), TE (240-300ms), FOV (300mm) and slice sickness 1mm, those examinations were performed using siemens (0.32T) permanent magnetom, Phil...
This study was conducted in different hospitals in Khartoum state. The study involved two hundred stool samples collected from 100 patients with irritable bowel syndrome (IBS) and another 100 as controls, during the period between February and June (2016). The results showed that 51 (51%) of irritable bowel syndrome patients as well as 33 (33%) of the control were harboring gastrointestinal parasites. The study revealed that Entamoeba histolytica was seen in 22% of the IBS cases follow...
ABSTRACT Normal reference values of haemostatic profile are frequently needed to assist in diagnosis and management of bleeding disorders. Because of the anatomical and physiological differences between neonates and adults, it is essential to know the reference range of coagulation profile in neonates in the first week of life. The aim of this study is to establish a normal reference range for coagulation profile in normal full-term neonates in the first week of life in Lagos-Nigeria. This i...
ABSTRACT Background: The rhesus (Rh) blood group system is one of the most polymorphic and immunogenic blood group systems known in humans. The common potent Rh antigens reside on the RH polypeptides. The antigenic expression is controlled by the RHD and RHCE genes, linked in tandem on chromosome 1. The D antigen is clinically the most important because of its high immunogenicity and polymorphism. HDFN is perpetuated by foeto-maternal rhesus antigens incompatibility. Aim: The aim of this stu...
ABSTRACT The fusion between the “breakpoint cluster region” gene (BCR) and Abelson gene (ABL1) is the molecular hallmark of most cases of chronic myeloid leukaemia and some cases of acute lymphoblastic leukaemia. The objective of this study was to detect BCR-ABL1 in saliva of known CML patients collected in Oragene-RNA kit (DNA Genotek, Canada) and to see if mRNA could be preserved for a longer period in the saliva samples than in blood samples. A comparison of the BCR-ABL ratios in bloo...
Abstract Fifty (50) Non-diabetic Hypertensive Patients in the medical out-patient (MOP) department of University of Nigeria Teaching Hospital (UNTH), Ituku Ozalla, Enugu, Nigeria aged 40-78 years comprising 25 males and 25 females were investigated. Also fifty age and sex-matched apparently healthy subjects served as the control group. The following variables were determined using standard methods: prothrombin Time, Activated partial Thromboplastin Time, Fibrinogen Assay, platelet Count, Fas...
Abstract Prostate cancer is the second highest cause of death due to cancers in men. The risk of developing it increases with age and the highest incidence is observed in men above the age of 50 years. In black men, the estimated lifetime risk of being diagnosed with prostate cancer is 20.6% while the lifetime risk of death due to it is 4.7%. The current standard tests for the diagnosis of prostate cancer are the serum prostate-specific antigen (PSA) test, digital rectal examination (DRE) and...
ABSTRACT The ABH-lectin activity was carried out on fourteen (14) tropical edible fruits sourced from Terminus market in Jos, Plateau State, Nigeria. Haemagglutination techniques were carried out on fruit juices and seed/nut extracts using standard A, B, O(H) cells. Three hundred (300) subjects administered with questionnaires were tested for ABH-fruit incompatibility. Cashew; red and yellow (Anacardiumoccidentale), apple; green (Maluspumila) and guava; red (Psidumguajava) juices agglutin...
ABSTRACT Background: Benign prostatic hyperplasia is a well-known and commonly diagnosed urological condition in the aging male population, which affects over 50% of men in their 60s and increased to 90% by the age of 85 years. The condition is normally accompanied by lower urinary tract symptoms that impacts negatively on the quality of life. Upon all the problems that BPH cause in the life of men, the exact aetiology is unknown. Several mechanism have been mentioned that contribute to the p...
ABSTRACT Background: Routine empiric antibiotic therapy is common in patients living with HIV/AIDS. Such routine antibiotic regimen could lead to selection of multidrug resistance especially ESBLs in hitherto drug sensitive intestinal colonizing flora. There is paucity of data to describe intestinal carriage of ESBL-producing enterobacteria in HIV/AIDS patients. Aim: This study was designed to examine HIV/AIDS patients for faecal carriage with extendedspectrum beta-lactamase producing enterob...
ABSTRACT Background; In most laboratories, Coagulase Negative Staphylococci (CoNS) are treated as contaminants and therefore follow ups with regards to species detection and antimicrobial susceptibilities are not done. There is a growing incidence of antimicrobial resistant CoNS across the globe making infections difficult to treat. Data on these resistant pathogens are limited in Africa in general and Ghana in particular. It is therefore important to characterize CoNS with respect to their a...
ABSTRACT Perilipins are phosphoproteins that are found in fat cells where they are restricted at the uppermost layer of lipid droplets. Over-expression of perilipin proteins in fat cells cause the storage of triacylglyceride (TAG) to increase in connection with a reduction in fats and lipd breakdown that causes increases in weight and type 2 diabetes and cardiovascular diseases. There are two types of perilipin which have a common N-teminal amino acids sequence which are perilipin A (P...
ABSTRACT BACKGROUND: Malaria rapid diagnostic tests (MRDTs) are important for malaria disease management. However, performance of the RDTs is affected when the targeted antigens in the parasite have a variation or are altogether absent. The most common parasite target antigen in RDTs, Plasmodium falciparum histidine-rich protein 2 (HRP2), has been reported to be absent in some P. falciparum parasites. Loss of the pfhrp2 in P. falciparum parasites affects the accuracy of PfHRP2 based RDT ...