Abstract Background: Pulmonary tuberculosis (PTB) mortality remains high despite current availability of effective anti-TB drugs. This could be due to pathophysiological derangements that are not fully understood and managed during anti-TB therapy. The objective of this study was to evaluate the hematological changes in newly diagnosed PTB patients. Methods: 55 newly diagnosed PTB patients and 55 healthy controls were included in this cross-sectional non-randomized study. Complete hematologi...
Abstract Background Breast cancer is the most common female cancer worldwide. Its diagnosis and prognosis remain scanty, imprecise, and poorly documented. Previous studies have indicated that some genetic mutational signatures are suspected to lead to progression of various breast cancer scenarios. There is paucity of data on the role of AI tools in delineating breast cancer mutational signatures. This study sought to investigate the relationship between breast cancer genetic mutational prof...
The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world. Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, therefore bats could be the possible primary reservoir. The intermediate source of origin and transfer to humans is not known, howeve...
ABSTRACT Lemon grass (Cymbogon citratus) is an abundant, locally available plant. In this work, essential oil was extracted from it using solvent extraction method. In this work two methods of extraction was used, solvent extraction and enfleurage methods were used to extract essential oil from lemongrass. Solvent extraction method yielded 2.08% and effleurage method yielded 1.96% essential oil respectively. From the analysis solvent extraction gave the highest yield because of the less e...
ABSTRACT This project work titled “A feasibility study on the production of yogurt” a case study of Fan Milk Nigeria Plc, Oregun – Ikeja has been written to p-rovide an intensive knowledge of the practical aspect of producing yogurts in addition to the theories which involves the economical and nutritional benefits of yogurts already learnt by the researchers. This study will look into the production processes with Fan Milk Nigeria Plc, Oregun – Ikeja. The coverage of the subject ma...
ABSTRACT Trichuris trichiura, also known as the human whipworm, is a roundworm that causes trichuriasis in humans. It is referred to as the whipworm because it looks like a whip with wide handles at the posterior end. The main objective of this study was to determine prevalence and risk factors associated with Trichuris trichiura among patients attending health care at AL-Shifa Health Center in Yaqshid, District. During this study, 100 stool samples were examined, which were collected from pa...
ABSTRACT Spectrophotometry is a powerful analytical technique that plays a pivotal role in various scientific disciplines, including medicine, chemistry, biology, physics, and environmental science. This seminar presentation offers a comprehensive overview of spectrophotometry, exploring its fundamental principles, applications, and technological advancements in various sectors. The presentation begins by delving into the basic principles of spectrophotometry, elucidating the interaction of...
ABSTRACT In a comprehensive study to assess the effects of botanicals and biocontrol agents on growth and aflatoxin (AF) production by Aspergillus flavus (A. flavus) infecting maize, a total of 1143 maize samples, collected in eighteen batches of five maize varieties (yellow, white, pop, variegated and mixed) from northern and southern parts of Nigeria were investigated between June 2011 to December 2013. Samples collected from field, 414 (36.2%) and stored batches, 729 (63.8%) were cultured...
ABSTRACT The effect of Ocimum tenuiflorum on hematological parameters in immunosuppressed albino rats was investigated in this study. The aqueous (AE) and methanol extract (ME) of the leaf were obtained. Acute toxicity study was done to determine the LD50 of the leaf extract. Rats of mixed sexes, aged 2- 3months, weighing 150 to 240 grams were used. The rats were divided into 8 groups A-H of four rats each. Group A served as normal control. Immunesuppression was induced using 3mg/kg bodyweig...
ABSTRACT Malaria is characterized by marked changes in cytokine production from immune responses to infection (Jurgen, 2007). Genetics influences these variations in cytokine expression and ABO blood group and haemoglobin phenotype are genetic expressions (Deepa et al, 2011). Acute phase proteins may also be involved in cytokine induced replication of inflammatory processes (Warren (2010). This case controlled study involving children with plasmodium falciparum malaria (PFM) in Nnewi, Nigeri...
Abstract Human Immunodeficiency Virus ( HIV) is global and serious problem , with increase in mortality and morbidity worldwide. This was prospective , descriptive and cross sectional study aimed to assess the level of HIV Ab using the ICT and ELISA for detecting Ab and Ag (p24) .It was conducted among Screening patient in Khartoum state (National Public Health Laboratory) from 1 April to 30 June (2015) on a total of eighty nine (n=89)to compare the sensitivity and specificity of immunochro...
Abstract This is a prospective case control study to investigate the effect of alcohol consumption on complete blood count (CBC) of alcohol consumers in Khartoum State from April to July 2014.The participants were 80 apparently healthy adult males; 50 of them are alcohol consumers and 30 are non-alcoholic (control).Their age was (41 ±7.3years).A questionnaire was constructed to obtain information about the participants after an informed verbal consent from all the participants. Ethical appr...
ABSTRACT Molecular basis of immunological dysfunction in people living with HIV and AIDS was studied among HIV-positive people attending clinics at the University of Nigeria Teaching Hospital Ituku-Ozalla, Annunciation Specialist Hospital Emene, Mother of Christ Specialist Hospital and Enugu State University Teaching Hospital, all in Enugu metropolis. A total of 90 subjects recruited for the study were divided into three groups: 30 diagnostically positive HIV subjects (A), 30 HIV-positive sub...
ABSTRACT Pleurotus tuberregium is a common mushroom which is used as food or medicine, more commonly as a vegetable soup thickener. This study investigated the presence of heavy metals in wild samples of pleurotus tuberregium sclerotia consumed within our localities, compared the degree of heavy metal contamination of the samples, investigated the presence of heavy metals in the serum of albino rats due to its consumption and the effects of its consumption on blood, bone marrow, liver and kid...