Optometry Research Papers/Topics

First report of Phasey bean mild yellows virus in Kenya with a new host record

Abstract Genome studies in Australia reported a novel virus, Phasey bean mild yellows virus (genus Polerovirus; PBMYV), in mixed infections with Bean leaf roll virus, Faba bean polerovirus 1, Soybean dwarf virus and Turnip yellows virus naturally infecting phasey bean (Macroptilium lathyroides) (Sharman et al., 2021). Transmission studies with Aphis craccivora and by grafting with infected scions identified fabaceous hosts including chickpea, faba bean and pea as additional hosts of PBMYV (W...

Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to Plasmodium falciparum infections and severe malarial anemia in kenyan childr

Abstract Background: Severe malarial anemia (SMA; Hb < 5.0 g/dl) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions such as western Kenya. Methods: We investigated the relationship between two novel complement component 5 (C5) missense mutations [rs17216529:C>T, p(Val145Ile) and rs17610:C>T, p(Ser1310Asn)] and longitudinal outcomes of malaria in a cohort of Kenyan children (under 60 mos, n = 1,546). Molecular modeling was used to...