Prevalence, Treatment, And Gametocyte Carriage In Cidldren With Malaria At Ishaka Adventist Hospital

TABLE OF CONTENTS

DECLARA TTON .................................................................... i

DEDIC AT! ON .............................................................................. !

ACKNOWLEDGEMENT .................................................. 2

ABSTRACT ............................................................... 6

CHAPTER I : .................................................................... 7

1.0 Introduction .................................... 7 1.1
 Backgro............................................ 7

1.1 Background .................................................................. 7

1.2 Problem statement ........................................................... 8

1.3.0 General objectives ....................................................... 9

1.3.1 Specific objectives ......................................................... 9

1.4.0 Study hypothesis ....................................................... 9

1.4.1 Null hypothesis ........................................... 9

1.4.2 Alternative hypothesis ................................................ 9

1.5.0 Scope of the Study ................................................................ 9

1.5.1 Time Scope ..................................................................... 9

1.5.2 Content Scope ........................................................... 9

1.5.3 Geographical Scope .................................................... 9

1.6 Justification the study ................................................... 10

CHAPTER 2: ............................................................................ 11

2.0 LITERATURE REVIEW ..................................................... 11

2.1 Malaria prevalence ....................................................... 11

2.2 Malaria and gametocyte carriage .......................................... 12

2.3 Malaria treatment. ..................................................... 13

CHAPTER 3: ........................................................................ 15

3.0 METHODOLOGY: ................................................................... 15

3.1 Study Design ............................................................ 15

3.2 Study Setting ............................................................ 15

3.4 Stndy Population ...................................................... 15

3.5 Sample Size ................................................................... 15

3.6 Inclusion Criteria ..................................................................... 16

3.7 Exclusion Criteria ....................................................................... 16

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3.8 Sampling Techniques .......................................................... 16

3.9 Data Collection Procedures: .............................................. 16

3.9.1 Questionnaire ............................................................ 16

3.9.2 Laboratory Investigation .............................................. 17

3.10 Outcome Measures ............................................................. 19

3.11 Data Analysis Procedures .................................................. 19

3.12 Ethical Considerations .............................................. 19

4.0 Study findings ......................................................... 20

4.1 Introductions ................................................................. 20

4.1 Study Findings ......................................................................... 20

Discussions ................................................................................. 31

5.0 Introductions ........................................................... 31

5.1 Demographic charateristicts ................. : ................... 31

5.2 Prevalence rate of malaria among children at Ishaka Adventist Hospital.. ............................. 31

5.3 treatment given to children with malaria at Ish aka Adventist Hospital .................................. 32

5.4 To determine the gametocyte carriage in children with malaria at Ishaka Adventist Hospital........................... 32

5.3 conclusion .......................................................................... 32

5.4 recommendation ......................................................... 'ljl

CHAPTER SIX ..................................................................... 34

REFERENCES ............................................................... 34

CHAPTER SEVEN ................................................................. 36

APPENDIX I ....................................................................... 36

APPENDIX 2: .................................................................. 39

APPENDIX 3 ...................................... Error! Bookmark not defined.

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ABSTRACT

Background Malaria is endemic in I 07 countries and territories in tropical and subtropical regions, with

sub-Saharan African hit hardest and is highly endemic in 95% of Uganda with

approximately 90% of the population (estimated at 32 million people) at risk. The remaining

5% of the country consists of unstable and epidemic-prone transmission areas in the

highlands of the south and west, along the eastern border with Kenya, and the northeastern

border with South Sudan. Malaria transmission is persistently high in some areas of northem

Uganda.

Methodology

A prospective cross sectional study was carried out involving_ both qualitative and quantitative

methods of data collection

Results

The study found out that the prevalence rate of malaria among children treated at Ishaka

Adventist Hospital was 23%, all children were given paracetamol most children were given

coartem (Artmether Lumefantrine), some few were given iv attesunate and quinine Health

Centre and the gametocytes carriage in children with malaria at lshaka Adventist Hospital

was 21%.

Conclusion

The prevalence rate of malaria among children treated at lshaka Adventist Hospital was low

coartem (Artmether Lumefantrine), iv artesunate and quinine were the drugs used to treat

malaria

The gametocytes carriage in children with malaria at Ishaka Adventist Hospital was low.

The altemative hypothesis that determination of the prevalence, treatment, and gametocyte

carnage is important in reducing the morbidity and mortality of children with malaria

remains

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