Samuel Chukwujekwu

EFFECTS OF SPONDIAS MOMBIN ETHANOLIC LEAF EXTRACT ON HAEMOSTATIC AND HAEMATOLOGICAL PARAMETERS OF ALLOXAN-INDUCED DIABETIC MALE WISTAR RATS.

Page|3CHAPTERONE1.1INTRODUCTION.Haemostasisisthatbodilymechanismthatpreventsexcessivebloodlossfromthebodyduringdamagetotissues.Thehaemostaticsystemrepresentsadelicatebalancebetweenpro-coagulantandanti-coagulantmechanismslinkedtoaprocessoffibrinolysis(Sandhyarani&Kumar2014).Therearefivemajorcomponentsinvolvedinthehaemostaticsystemandtheseincludes;platelets,coagulationfactors,coagulationinhibitors,fibrinolysisandbloodvessels(Guyton&Hall2006).Haemostasisisalifesavingprocessandso,thestudyofsubsta...