Assessment Of Serum Uric Acid And Albumin Among Sudanese Patients With Deep Vein Thrombosis

Abstract

Background: Deep venous thrombosis (DVT) is a common condition estimated to affect around 100000 patients each year in the UK.. it is associated with increased mortality in some thrombotic disorders .

Objectives: This study conducted to assess the serum uric acid, and albumin in DVT patients.

Methods: This was case control study based on 50 DVT patients as cases, and 50 apparently healthy individuals as controls (age and gender were matched between two groups) Blood sample was taken from each participant to prepare the serum . The serum uric acid and albumin concentrations were measured using Bio system BTS-400 spectrophotometer.The data obtained was subjected to analysis using statistical packaged for social science computer program (SPSS version 20 ).

Results: The result showed that, (70%) of patients at age range between (20-40) years, (24%) between (41-60)years and (6%) between (61-80) years. (80%) of patients were females while (20%) were males. The levels of albumin was significantly increase in DVT patients compared to control group and there was no significant difference in uric acid level in DVT patients compared to control group : albumin (mean ± SD: 4.1 ± 0.65 g/dl versus 3.5±0.49 g/dl, P .value= (0.000), uric acid (mean ±SD: 3.85 ±1.8 mg/dl versus 3.88 ± 1.2, P .value = (0.929). There were negative correlation between albumin , serum uric acid and age. (r = -0.334 , p .value=0.018 and r =-0.339 p .value=0.016 )respectively , there were no correlation between the albumin ,Serum uric acid and duration of disease (r= - 0.026, P. value =0.858) , (r= - 0.018, P. value =0.903) respectively .

Conclusion: The results of this study concluded that , the levels of albumin is increased in DVT patients and the level of it increased in females than males. There were negative correlation between albumin, serum uric acid and age.