Biological Science Research Papers/Topics

HIV Virologic Failure among Patients with Persistent Low-Level Viremia in Nairobi, Kenya: It Is Time to Review the >1000 Virologic Failure Threshold

Abstract Persistent low-level viremia (PLLV) of 200-999 copies/ml has been reported as a risk factor for HIV virologic failure (VF). This retrospective study was aimed at characterizing patients with PLLV, determining factors associated with VF, and determining the effect of regimen change. Data were extracted from electronic medical records for HIV care and treatment. Patients’ characteristics (N = 705) were as follows: a mean age of 42 years, majority female (55%), and 51% married. A maj...

Nematode assemblages, food web indices and metabolic footprints in maize-pigeon pea agro-ecosystems.

Abstract Pigeon pea (Cajanus cajan L.) and maize (Zea mays L.) are important food crops in developing countries due to their multiple benefits. However, their production is constrained by plant-parasitic nematodes (PPN) which cause significant yield losses. Understanding the nematode-based soil food web structure in maize-pigeon pea agroecosystems will allow sustainable PPN management by improving soil health. This study explored nematode community assemblages, indices and metabolic footpr...

Contribution of Indigenous Innovations for Mitigating Fall Armyworm (Spodoptera frugiperda J. E. Smith) among Maize Farmers for Improved Food Security

Abstract/Overview Fall armyworm (FAW) is a new invasive pest that causes economic damage to a wide variety of crops. This pest is estimated to reduce maize yields by about 60%. FAW could cause crop losses of up to US$13 billion annually across sub- Saharan Africa, threatening the livelihoods of millions of resource-poor farmers worldwide. Governments have warned against the indiscriminate use of chemical pesticides that could undermine pest control strategies for smallholder farmers who r...

Woody Species Composition, Stand Structure and Regeneration Status of Londiani Forest in Kenya

Abstract first_pagesettingsOrder Article Reprints Open AccessArticle Woody Species Composition, Stand Structure and Regeneration Status of Londiani Forest in Kenya by Evalyne Kosgey Chepkoech 1,*,Humphrey Agevi 1,2ORCID,Henry Lung’ayia 1 andHarrison Mugatsia Tsingalia 1 1 Department of Biological Sciences, Masinde Muliro University of Science and Technology (MMUST), Kakamega P.O. Box 190-50100, Kenya 2 Institute of Indigenous Knowledge, Cultural Studies and Climate Change, Masinde Muliro U...

Genetic Diversity and Population Structure of Doum Palm (Hyphaene compressa) Using Genotyping by Sequencing

Abstract Doum palm (Hyphaene compressa) is a perennial economic plant primarily growing in Kenya’s Arid and Semi-Arid Lands (ASALs). It is heavily relied upon for food, animal feed, construction materials and medicine, making it an ideal plant for resource sustainability. However, the limited information on its genetic resources has hindered its breeding and conservation studies. This study used the genotyping by sequencing approach to identify Single Nucleotide Polymorphisms. These SNPs w...

Small Farm Holder Cropping Systems Influence Microbial Profiles in an Equatorial Rainforest Agroecosystem

Abstract The metabarcoding of prokaryotic and fungal (Ascomycota only) ribosomal DNA was used to describe the microbial communities in soils of a remnant equatorial rainforest, maize–bean intercrop, and sugarcane in western Kenya. Cropping systems influenced the microbial community composition and functional traits (energy source and nutrient cycling) of bulk soil in each crop. Microbial richness and diversity tended to increase with cultivation intensity. The soil of the maize–bean inte...

Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden malaria and HIV region

Abstract Plasmodium falciparum infections remain among the leading causes of morbidity and mortality in holoendemic transmission areas. Located within region 5q31.1, the colony-stimulating factor 2 gene (CSF2) encodes granulocyte–macrophage colony-stimulating factor (GM-CSF), a hematopoietic growth factor that mediates host immune responses. Since the effect of CSF2 variation on malaria pathogenesis remains unreported, we investigated the impact of two genetic variants in the 5q31.1 gene r...

TRADE-OFFS IN TREE SPECIES SELECTION AND CARBON OFFSET ON FARMS ADJACENT TO KAKAMEGA-NANDI FOREST ECOSYSTEM IN KENYA

Abstract Background: Growing of trees on-farms has contributed significantly in easing pressure on the Kakamega–Nandi Forest Ecosystem. There are however concerns that Eucalyptus species is becoming the dominant tree in this landscape and may have adverse effects on the environment. Objectives: To determine the trade-offs in tree species selection and carbon offsets on farms in the margins of the Kakamega - Nandi Forest Ecosystem. Methodology: It employed a nested experimental design where...

Production of Organic Compost from Water Hyacinth (Eichhornia crassipes [Mart.] Solms) in the Lake Victoria Basin: A Lake Victoria Research Initiative (VicRes

Abstract The Lake Victoria Basin (LVB) supports one of the poorest and most populous rural populations in the East Africa region. The dipping fsh population has forced the community around the Lake Victoria to turn to farming for food crops to meet its daily food demands. Chemical fertilizer which is readily available has been the alternative source of improving soil condition which has led to eutrophication of the lake waters causing the temperature to rise in the process affecting most fre...

In Silico Models for Anti-COVID-19 Drug Discovery: A Systematic Review

Abstract The coronavirus disease 2019 (COVID-19) is a severe worldwide pandemic. Due to the emergence of various SARS-CoV-2 variants and the presence of only one Food and Drug Administration (FDA) approved anti-COVID-19 drug (remdesivir), the disease remains a mindboggling global public health problem. Developing anti-COVID-19 drug candidates that are effective against SARS-CoV-2 and its various variants is a pressing need that should be satisfied. This systematic review assesses the existin...

Molecular Characterization and Mineralizing Potential of Phosphorus Solubilizing Bacteria Colonizing Common Bean (Phaseolus vulgaris L.) Rhizosphere in Western Kenya

Abstract Phosphorus solubilizing bacteria (PSB) are a category of microbes that transform insoluble phosphates in soil into soluble forms that crops can utilize. Phosphorus in natural soils is abundant but poorly soluble. Hence, introducing PSB is a safer way of improving its solubility. The aim of this study was to genetically characterize and determine the mineralization capability of selected PSB colonizing rhizospheres of common beans in Western Kenya. Seven potential phosphorus solubili...

Abundance and Symbiotic Rhizobia Colonizing Soybean (Glycine max) in Soils of Kakamega County, Western Kenya

Abstract Identification of effective indigenous rhizobia strain nodulating soybean (Glycine max) was conducted in Kakamega County, Western Kenya. This study was carried out to establish the abundance and symbiotic efficiency of native rhizobia strains in soil samples collected from 12 sites in four agroecological zones within the region. The MPN enumeration technique was used to estimate the indigenous rhizobia numbers and showed that 54% of the sampled sites had high abundance. Rhizobia num...

Effects of Sand-Harvesting on River Water Quality and Riparian Soil Physico-Chemical Properties

Abstract The widespread distribution of river sand-harvesting activities continues to degrade river water quality and the surrounding riverine environments. This study determined practical effects of sand-harvesting on two rivers in Kakamega County Kenya. Water samples were tested for turbidity and total suspended solids (TSS). For riparian soils, nitrogen (N), phosphorus (P), pH, organic carbon (OC), moisture content and textural class were determined on composite samples obtained from the ...

Soil Microbes Determine Outcomes of Pathogenic Interactions Between Radopholus similis and Fusarium oxysporum V5w2 in Tissue Culture Banana Rhizospheres Starved of Nitrogen, Phosphorus, and P

Abstract The contributions of soil biota toward outcomes of pathogenic interactions between Radopholus similis and Fusarium oxysporum V5w2 in tissue culture banana plants starved of nitrogen (N), phosphorus (P), and potassium (K) were investigated. The study was based on three screenhouse factorial experiments (2 × 2 × 2) comprising of potted banana plants with or without R. similis, with or without F. oxysporum V5w2, and either grown in sterile or non-sterile soil. All plants in each of t...

The Role of Innovative Teaching and Learning Methods Towards the Classification of Living Things: A Review

Abstract Biology continues to present difficulties in teaching and learning. Among other biology domains classification of living things is considered to be one of the challenging subjects as different studies indicated students’ misconceptions in the test to classify both plants and animals. Inadequate teaching methods were the core source of these challenges which were also found to lead to poor performance in schools. This review paper shows the role of active teaching methods to improv...


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