This study was conducted as retrospective case study aimed to determine the frequency of HPV (16 and 18) and EBV among Sudanese with esophageal cancer using immunohistochemistry and PCR. The study included one hundred and two 102 paraffin blocks from patients previously diagnosed as esophageal cancer from Khartoum Sudan, in Ibn Sina hospital, khartoum hospital, soba teaching hospital, military hospital and national health laboratory. Their age ranged from 21 to 98 years old with mean age 59 years. 46 (45 %) were female and 56(55%) were male. The data were collected from examination of biopsies and patients records. All esophageal cancer biopsies were examined and classified into histopathological pattern using hematoxylin & eosin standard method. 91(89.2%) samples were esophageal squamous cell carcinoma and 11(10.8%) samples were adenocarcinoma. Regarding IHC staining for HPV (16 and 18), positive findings were revealed 14 (13.7%) and couldn't be disclosed in 88 (86.3%) of the study subjects, the highest positive results were found in age group 66-75 years, of the 56 males with esophageal cancer, 7 (12.5%) samples were identified with HPV16, 18 infection and the remaining 49(87.5%) samples found without HPV (16 and 18) infection. Of 46 females positive revealed in 7(13%) samples and the remaining 39(87 %) samples were found negative for HPV (16 and 18).
Babikir, M (2021). Frequency of Human Papilloma Virus (16 and 18) and Epstein Bar Virus among Sudanese patients with Esophageal Cancer using Immunohistochemistry and Polymerase Chain Reaction. Afribary. Retrieved from https://track.afribary.com/works/frequency-of-human-papilloma-virus-16-and-18-and-epstein-bar-virus-among-sudanese-patients-with-esophageal-cancer-using-immunohistochemistry-and-polymerase-chain-reaction
Babikir, Mohamed "Frequency of Human Papilloma Virus (16 and 18) and Epstein Bar Virus among Sudanese patients with Esophageal Cancer using Immunohistochemistry and Polymerase Chain Reaction" Afribary. Afribary, 12 May. 2021, https://track.afribary.com/works/frequency-of-human-papilloma-virus-16-and-18-and-epstein-bar-virus-among-sudanese-patients-with-esophageal-cancer-using-immunohistochemistry-and-polymerase-chain-reaction. Accessed 20 Nov. 2024.
Babikir, Mohamed . "Frequency of Human Papilloma Virus (16 and 18) and Epstein Bar Virus among Sudanese patients with Esophageal Cancer using Immunohistochemistry and Polymerase Chain Reaction". Afribary, Afribary, 12 May. 2021. Web. 20 Nov. 2024. < https://track.afribary.com/works/frequency-of-human-papilloma-virus-16-and-18-and-epstein-bar-virus-among-sudanese-patients-with-esophageal-cancer-using-immunohistochemistry-and-polymerase-chain-reaction >.
Babikir, Mohamed . "Frequency of Human Papilloma Virus (16 and 18) and Epstein Bar Virus among Sudanese patients with Esophageal Cancer using Immunohistochemistry and Polymerase Chain Reaction" Afribary (2021). Accessed November 20, 2024. https://track.afribary.com/works/frequency-of-human-papilloma-virus-16-and-18-and-epstein-bar-virus-among-sudanese-patients-with-esophageal-cancer-using-immunohistochemistry-and-polymerase-chain-reaction