Abstract
Preliminary bioassay analysis was done on all parts of the three plants under study as explained in section 4.2.1.
The antiplasmodial activity of the DCM extract of the leaves of E. abyssinica was significantly high (p≤0.05) against W2 and D6 clones of P. falciparum with IC50 values 165.1 and 215.1 g/mL, respectively. Similarly, the DCM extract of the stem bark of L. eriocalyx showed high activity (p≤0.05) of 423.0 and 365.2 g/mL against the two clones. Likewise, the DCM extract of the root bark of A. ovalifolius also exhibited high activity agaist the W2 clone (p≤0.05) with IC50 value of 234.0 g/mL.
Moderate larvicidal activity against A. gambie was shown by the DCM extract of L. eriocalyx with 53.0±0.02% mortality whereas the DCM and MeOH extracts from A.ovalifolius were highly active in larvicidal and mosquitocidal assays with a knock down of 87.7±0.01 and 88.5±0.01 % mortality, respectively. Likewise, the larvicidal and mosquitocidal activities of the DCM and MeOH extracts of E. abyssinica were moderate with 65.1±0.4 and 65.5±0.14% mortality, respectively.
Stephen, A. (2021). The Phytochemistry and the bioactivity of L. eriocalyx, A. ovalifolius and E. abyssinica all belonging to the family Fabaceae. Afribary. Retrieved from https://track.afribary.com/works/the-phytochemistry-and-the-bioactivity-of-l-eriocalyx-a-ovalifolius-and-e-abyssinica-all-belonging-to-the-family-fabaceae
Stephen, Adamu "The Phytochemistry and the bioactivity of L. eriocalyx, A. ovalifolius and E. abyssinica all belonging to the family Fabaceae" Afribary. Afribary, 07 May. 2021, https://track.afribary.com/works/the-phytochemistry-and-the-bioactivity-of-l-eriocalyx-a-ovalifolius-and-e-abyssinica-all-belonging-to-the-family-fabaceae. Accessed 24 Nov. 2024.
Stephen, Adamu . "The Phytochemistry and the bioactivity of L. eriocalyx, A. ovalifolius and E. abyssinica all belonging to the family Fabaceae". Afribary, Afribary, 07 May. 2021. Web. 24 Nov. 2024. < https://track.afribary.com/works/the-phytochemistry-and-the-bioactivity-of-l-eriocalyx-a-ovalifolius-and-e-abyssinica-all-belonging-to-the-family-fabaceae >.
Stephen, Adamu . "The Phytochemistry and the bioactivity of L. eriocalyx, A. ovalifolius and E. abyssinica all belonging to the family Fabaceae" Afribary (2021). Accessed November 24, 2024. https://track.afribary.com/works/the-phytochemistry-and-the-bioactivity-of-l-eriocalyx-a-ovalifolius-and-e-abyssinica-all-belonging-to-the-family-fabaceae