Microbiological Analysis and Susceptibility Pattern of Bacteria Isolated from Ratus rattus and Felis catus Faecal Pellets from Residenal Houses of Akungba Communities in Ondo State, Nige
Rats have become household commensals that are found in resi- dential areas and offices. Cat faeces and rat faecal pellets are in every corner of the house especially in the food stores and this may pose a serious hazard because the faeces may contain microorganisms that are both pathogenic to humans and resistant to several classes of antibiotics. The aim of this study was to evaluate the potentials for zoonotic infections and for the presence of antibiotic resistant bacteria in rat faecal p...
Antimicrobial Activity, Chemical Compositions and Proximate Analysis of Ixora Coccinea L. Leaves on Some Clinical Pathogens
Plants derived bioactive compounds have been the centre of recent owing to their health promoting effects. An attempt was made in evaluating the phytochemical, minerals, proximate and anti-microbial activity of analyses standard agar well diffusion method saponins, tannins, flavon minerals analysis revealed the presence of manganese and phosphorus. Highest mineral content was recorded in magnesium (21. Proximate analysis showed the presence of ash (10.3%), moisture (7.10%), protein (16.45%), ...
Antimicrobial Properties, Phytochemical Composition,and Phenotypic Resistance Pattern of Selected Enteropathogenic Microorganism on Ageratumconyzoides (Goat Weed) Leaf Extract
The aim of this study is to determine the phytochemical composition, antimicrobial properties and phenotypic resistance pattern of selected enteropathogenic micro organism on Ageratum conyzoides leaf extract. Enteropathogenic isolates were collected from Adekunle Ajasin University Health Centre, Akungba Akoko, Ondo State and were identified using Microbact™ 24E Identification kit. Antibiotic sensitivity testing was carried out against the enteropathogenic organism using Kirby-Bauer disc dif...
Comparative Study Between the Eect of Parkia Biglobosa (JACQ) benth and Conventional Antibiotics Against Multiple Antibiotic Resistant Uropathogenic Bacteria (MARUB)
The purpose of this work is to compare the effect of convectional antibiotics with medicinal plant (Parkia biglobosa (Jacq.)Benth) against multiple antibiotics resistant Uropathogenic bacteria isolates.(MARUB), which was isolated from basically two hospital in Ondo State, Nigeria. The two hospitals are Gani Fawehinmi Diagnostic center, Ondo and Federal Medical Center, Owo between July, 2017 and October, 2017. fifty two (52) Gram negative bacteria isolated from urine of UTIs patient at the Gan...
Zones of Inhibition and Molecular Docking (In-silico Approach) of Piptadeniastrum africanum Extracts on Clinical and Multiple Antibiotic Resistant Isolates
The use of plants as medicines is an ancient practice common to especially Nigeria and Africa at large. The purpose of this research work is to evaluate the zones of inhibition, phytochemical screening and molecular docking (In-silico Approach) of Piptadeniastrum africanum against selected clinical and multiple antibiotic resistant isolates. Using agar well diffusion method, the antimicrobial activity of the stem bark and leaf extracts of Piptadeniastrum africanum was assayed against Escheric...
Evidence for the Immune Toxicity of Green Tea Polyphenols: A Computational Study
Adverse drug reactions (ADR) triggered by a drug or its metabolites is an essential aspect of the post-clinical phase in the drug discovery pipeline. The pathophysiology of ADRs has been described in two ways; expected and idiosyncratic. In the current study, we deployed valid computational tools to predict the ability of eight green tea polyphenols to favourably interact with HLA-B*57:01 and mediate idiosyncratic ADRs. First, we deployed molecular docking to understand the free energy profil...
Bio-activity and Spectral Analysis of Gas Chromatography/Mass Spectroscopy (GCMS) Profile of Crude Spomdias mombin Extracts
The purpose of this work is to determine the biological activity and spectral analysis of Gas chromatography/mass Spectroscopy (GC-MS) profile of crude extract of S monbin,S.mombin L. (Anacardiacaea) is a plant that grows in almost every part of the world. It is fruitferious decidous plant of about 20m high that grows in the rain forest of Africa. Smombin parts were harvested early in the morning into a polythene bag. S.mombin plant (1kg) each of the different plant parts was extracted with 3...
Qualitative and Quantitative Screening of Phytochemical Analysis of Spondias mombin (Linn.) Extracts (Root, Leaf and Stem Bark), A Useful Formulation in Drug Discovery
The objective of this is to determine the qualitative and quantitative screening of phytochemicalanalysis of Spondias mombin (Linn) extracts (root, leaf, and stem bark) using different extraction solvent. The root, leaf, and stem bark of Spondias mombin plant were harvested early in the morning into a polythene bag at Oja Oba market, IkareAkoko, Ondo State, a tropical rainforest of Nigeria with latitude (7.21692 North) and longitude (5.21561 East). The Spondias mombin. Powdered plant material...
Evaluation of Inhibitory Zone Diameter (IZD), Phytochemical Screening, Elemental Composition and Proximate Analysis of Crude Cleistopholis Patens Leaf
This purpose of this study is to determine the Inhibitory zone diameter (Izd), phytochemical screening, elemental composition and proximate analysis of crude Cleistopholis patens leaf, bark, aqueous and ethanol extracts on selected pathogenic isolates. The leaf and bark of Cleistopholis patens plants were obtained from a location in the southwestern part of Nigeria, in the tropical rainforest of Ikare Akoko, Ondo state and Ile Ife, Osun state, Nigeria. The six (6) bacterial isolates include E...
Toxicity Assessment of Stem Bark Extracts
Spondias mombin is depends on for various herbal remedies for the treatment of numerous health conditions. This study is to evaluate the In-vivo toxic effect of Stem bark extracts of Spondias mombin on in male and female albino rats. In-vivo toxicity test was carried out with modified Lorke’s method. Forty two (42) male and female albino rats weighing between 120-180g were used for the sub-chronic study. The rats were divided into five groups A- D (n=12). The albino rats were divided ...
Occurrence and Multiple Antibiotic Susceptibility Profile of Bacterial Pathogens Isolated from Patients with Chronic Respiratory Diseases
Abstract Objectives: The present study reported the antibiotic susceptibility profile and pattern of pathogens isolated from in- and out-patients with respiratory tracts infections. Methods: Sputum and throat swab samples were collected aseptically from subjects and cultured on the appropriate bacteriological media. Bacterial isolates were identified using biochemical tests and the identity of the isolate was later confirmed using Analytical Profile Index 20E kit. Antimicrobial susceptibilit...
Evaluation of Inhibitory Zone Diameter (IZD) of crude Spondias mombin (Linn.) extracts (root, leaf, and stem bark) against thirty infectious clinical and environmental isolates.
Abstract The purpose of this work is to evaluate the Inhibitory Zone Diameter (IZD) of crude Spondias mombin extracts against thirty infectious clinical and environmental organisms. The root, leaf and stem-bark of S. mombin were harvested and air-dried. The dried S. mombin was milled into powdered form using manual grinder. Powdered S. mombin (1kg) each of the different S. mombin parts was extracted with 3 L of 70% (v/v) ethanol, ethyl acetate and distilled water for 72 h at room temperature....
Antimicrobial, Phytochemical and Proximate Analysis of Four Nigerian Medicinal Plants on some Clinical Microorganisms
The increasing incidence of resistance to antibiotics among bacteria currently poses serious clinical and public health threat and has propelled efforts for newer alternatives to alleviate the problem. Extensive search and testing for different plants with potentials for antimicrobial properties is presently considered one of the most feasible options as substitutes to the current regimen of antimicrobials. We tested the antibacterial characteristic and the phytochemical composition of four c...
Phytochemical and Proximate
The purpose of this present study of seven Nigerian medicinal plants is to ascertain the medicinal, phytochemical and proximate constituents of the plants. The plants are .Acacia albida Del, Anchomanes difformis Engl, Boscia senegalensis, Bridelia ferruginea Benth, Ficus ingens (Miq.) Miq, Indigofera arrecta Hochst and Moringa oleifera Lam
Chewing Sticks and Oral Health Care in Owo Local Government, Ondo State
-the aim of this study is to carried out the Antimicrobial and phytochemical effect on five medicinal plants used as chewing sticks in Owo local government of Ondo State, Nigeria. Methods- The methods used for this study are antimicrobial assay, and phytochemical screening. The aqueous, ethanol and ethyl acetate extracts of the leaves, bark and roots of Distemonantus bentaminaitus , Anogeissus leiocarpus, Garcina kola, Piper guineense and Zanthoxylun Lessmamul for the po...
