ABSTRACT The reaction of α–toluenesulphonyl chloride with various readily available amino acids in basic medium afforded α–toluenesulphonamides (1a-k) which had their acid function subsequently amidated with diethyl amine to obtain their corresponding new N,Ndiethylalkanamido substituted α–toluenesulphonamide derivatives (2a-k). The electrophilic addition of p-toluenesulphonyl chloride with various amino acids' nitrogen gave p-tolylsulphonamide derivatives (4a-k) which upon further ...
ABSTRACT : H-bonds between neutral tyrosine and arginine in nonpolar environments are modeled by small-molecule phenol/guanidine complexes. From the temperature and concentration dependence of UV spectra, a value of ΔH° = −74 ± 4 kJ mol−1 is deduced for the formation of H-bonded parasol/dodecylguanidine in hexane. ΔE = −71 kJ mol−1 is computed with density functional theory (in vacuo). In dimethyl sulfoxide or crystals, (p-phenyl)alkylguanidines form head-to-tail homodimers with t...
Abstract Some of the physiochemical properties of Azadirachta indica Gum (Neem) Gum were studied. They include: moisture, ash, nitrogen hence the protein, pH value and specific optical rotation. The results show that: moisture content is 13.07%, ash content is 3.13%, Nitrogen content is 4.9%, protein is 32%, specific optical rotation is –65.5, and pH is 6.5. The number molecular weight of the sample was estimated using osmotic pressure measurement and found to be 4.0×106 g/mole. Thermodyn...
ABSTRACT The two natron samples were collected from different location of different environments .The samples were analysed qualitatively and quantitatively by standard methods of analysis to determine the chemical composition and the concentration of each component . The effect of natron on chemical structure of Toombak was studied. The analytical techniques used in this study are:- Flame Emission spectroscopy which was used to determine sodium and potassium ions, content and the results wa...
ABSTRACT Tomato leafminers, Tuta absoluta pose a control challenge due to resistance against many chemical pesticides including abamectin. In this study, new pesticide was developed by heating mixture of abamectin with neem oil at1:1 ratio. The heating of this mixture resulted to formation of a new compound which is highly biopotent than its constituent substances. This was confirmed by TLC spot formed at Rf 0.43. A leaf dip bioassay method was used to test toxicity against T. absoluta. Bio...
Abstract The aim of this study was to produce protein concentrate from the defatted kernel seeds of Balanites aegyptiaca and investigate its functional properties. The proximate chemical composition of the kernel seeds was determined. The results showed that the moisture, ash, crude protein, oil, and total carbohydrate contents were 3.89, 3.40, 42.41, 40.24 and 10.06% respectively. Protein concentrate was isolated by using alkaline extraction method which followed by isoelectric precipitatio...
ABSTRACT Numerous pyrazoline derivatives have been found to possess considerable biological activities; this fact had led us to model and design 120 trisubstituted 2-pyrazoline derivatives by linking pyrazoline ring system with different substituents in position 1, 3 and 5. Quantitative structure–activity relationship (QSAR) studies were carried out in order to get models that can be used to predict the anti-cancer activity of designed compounds. Data set of compounds consisting of pyrazol...
Abstract The present study was designed to investigate the antioxidant and antimicrobial activities of three Sudanese plants ; (Rheumpalmatum Rutagraveolens, Moringaperegrine) Phyto chemical study was conducted to detect thebioactive compounds. The crude ethanolic extract was partitioned successively by chloroform , ethyl acetate and n-butanol. Different fractoins were assessed for antimicrobial potency against standard bacterial strains: Gram positive ( Bacillus subtilis (NCTC8236), Staphyl...
ABSTRACT Aflatoxins are secondary metabolites produced by several species of Aspergillus fungi, which occur in food crops due to exposure of pre-harvest and post-harvest conditions. Complementary foods are considered an important source of energy, protein and fat for children aged between 6-24 months. The study was carried out to to determine levels of aflatoxins contamination of complementary flour composite and to explore the association between post-harvest handling practices and aflatoxi...
ABSTRACT The purpose of this study was to scrutinize the synergetic effects of the applied calcination temperature and holding time on the synthesis, characterization and photocatalytic antimicrobial applications of the developed polysaccharides based TiO2/Fe3O4 nanocomposite materials. Polysaccharide/TiO2/Fe3O4 nanocomposite materials were synthesized through modified sol-gel process using Titanium (IV) butoxide as precursor and Iron (II, III) oxide nanopowder as a support. The developed co...
Abstract A simple, precise, accurate and economical Reverse phase HPLC with a detection UV, method was developed and validated for the simultaneous determination of Bisoprolol fumarate and Hydrochlorothiazide in pharmaceutical formulations. Better separation was achieved using Cyanide column (250mm × 4.6mm, 5μm), maintained at 30 ͦC. The mobile phase was composed of buffer: methanol in the ratio of 82:18 (v/v), (the buffer was 1% solution of tetra butyl ammonium hydroxide, adjusted to pH ...
Abstract In this study, the fixed oil of Capsicum annum was extracted from seeds with n-hexane at room temperature. The oil was analyzed by gas chromatography-mass spectrometry (GC-MS) GC-MS analysis of the studied oil revealed the presence of 27 components. The major constituents were: octadecadienoic acid methyl ester (56.57%), hexadecanoic acid methyl ester (17.60%).Minor constituents were octadecenoic acid methyl ester (5.62%), methyl stearate (5.50%), and stigmasterol (2.37%). The oil w...
Abstract Hejamah or Blood cupping or bloodletting is a traditional Islamic treatment and a part of the prophetic medicine recommended by the prophet Mohammed, Peace Be upon Him .Hejamah is a form of cupping therapy (sucking blood out of the body for healing purposes).This study was carried out to evaluate the effect of hijamah on the liver concentrating specifically in the effect on liver enzymes (AST and ALT) and albumin protein levels. This study was accomplished in Khartoum state on rando...
ABSTRACT Dye-sensitized solar cells (DSSC) have received considerable attention for transferring clean solar energy into electricity over the previous decade. The Fluorescein dye is one among the metal-free organic dyes having a high potential for application in DSSC because of its environmentally friendly, less cost, easy fabrications. The aim of this study was to apply computational quantum calculation to understand the structural, molecular, electronic and photophysical properties of the ...
Abstract The oil of the medicinally important speciescorochorusolitorius was extracted by hexane and analyzed by GC-MS. The analysis revealed the presence of 22 components. The major components are: 9, 12- , hexadecanoic acid methyl .octadecadienoic acid (z,z)-,methyl ester 9, 12, 15-octadecatrien acid,2,3-dihydroxy ً.,methyl stearate .ester proply esterand eicosanoic acid, methyl ester. In cup plate ager diffusion bioassay corochorusolitorius oil showed excellent activity against Bacillus ...