Chemistry Research Papers/Topics

Chemical Characterization of Some Flavonoids from Trianthema prot ulacstrum and phoenix dactylefrera and Their Biological Activity

Abstract  In the present work, the stems of Trianthema portulacastrum and Phoenix d actylefera pollens were extracted with 95% ethanol at ambient temperature. Qualitative tests on alcoholic extract of Trianthema portulacastrum stems re vealed the presence of flavonoids, alkaloids, tannins, saponins, steroids, carb ohydrates and glycosides. The crude extracts of Trianthema portulacastrum and Phoenix daclylefera w ere initially purified by column chromatography. Further purification was ac com...

Synthesis, Characterization and Solvent Extraction Studies of 3,5-Bis[(2-Hydroxybenzylidene)-Amino]-Benzoic Acid and Its Co(Ii) and Ni(Ii) Complexes

ABSTRACT 3,5-Bis[(2-hydroxy-benzylidene)-amino]-benzoic acid (H2B) and its cobalt(II) and nickel(II) complexes were synthesized and characterized via: electronic, IR, 1 H NMR and 13C NMR. Job’s continuous variation method was used to determine the mole ratio for both metal complexes. Solvent extraction studies were carried out on H2B in 5% DMF with its cobalt(II) and nickel(II) complexes using CHCl3 as organic solvent; with variable condition effects of equilibrium time, buffer pH, mineral ...

Toxicological Studies on Organic Manures Derived from Municipal Solid Waste in Makindye, Rubaga and Kawempe Divisions of Kampala, Uganda

ABSTRACT The study was carried out to estimate the levels of contamination and marketability of organic compost manures, derived from Kampala municipal solid wastes (MSW), sold along roads in the various suburbs of Kampala. The organic composts were sampled from five locations: Kawempe (KWP); Bwaise (BWS); Kitebi (KTB); Wankulukuku (WKK) and Ggaba-Kansanga (GGK~. The overall quality of the compost manures was determined by investigating selected physicochemical, trace metals and fertilizing p...

Potentially Toxic Elements in Food Crops Grown on Urban Waste Dump-Sites A Case Study of Wakaliga Dump-Site, Kampala City, Uganda

ABSTRACT  This study aimed at investigating the seasonal variation in the levels of contamination in soils, food crops, and domestic spring water samples from Wakaliga dumpsite in Kampala. Potentially Toxic Elements (PTE) and physicochemical properties were analysed during the dry season (May-July 2017) and the wet season (September-November 2017) and the results compared to standard limits set by international and local agencies. The results obtained indicated that some of the elements were...

Assessment of Heavy Metal Pollution in Pece Channelized Stream Water Gulu Town, Northern-Uganda

ABSTRACT Water quality monitoring in developing countries is inadequate, especially in stream water affected by urban effluents and runoff. The purpose of this study was to investigate heavy metal contaminants in the Pece Stream water in Gulu Municipality, Northern-Uganda. Water samples were collected along the channel of Pece stream and other samples from Nakaseke River which served as a control site. Selected heavy metals (Zinc, Copper, Lead and Cadmium) were determined using Atomic Absorp...

Investigation of The Physicochemical, Microbial and Trace Metals Properties of Selected Packaged Drinking Water Sold in Kansanga, Kampala, Uganda.

ABSTRACT This study aimed at investigating the physicochemical and microbial properties of Packaged Drinking Water, sold in Kansanga, Kampala. Seventy-two samples were selected by systematic random sampling from local stores in the study area. Three types of Packaged Drinking Water samples (bottled, sachet and handtied) were selected. Spring water samples were used as control samples. Titrimetric techniques were used to determine the Chlorides, Alkalinity and the Total Hardness, while Nitroge...

Effect of sintering additives on the densification and dielectric properties of Sr0.5Ba0.5Nb2O6 ceramics synthesized by a soft-chemistry method

https://doi.org/10.1016/j.jssc.2022.123564._ Nano-crystalline Sr0.5Ba0.5Nb2O6 powders with addition of LiNbO3 or LiF as sintering additives were prepared by a soft-chemistry synthesis using polyethylene glycol. Calcination at 600 C results in nanocrystalline powders (dcryst. 30 nm) which were sintered between 1000 and 1300 C to ceramic bodies. By addition of 10 and 20 mol % LiNbO3, the sintering temperature was reduced by about 200 K and the activation energy of the initial stage of sintering...

In-vivo Anti-inflammatory Activity Studies of Some P-nitrophenyl Hydrazones

The goal of this research was the discovery of newer anti-inflammatory drug. Four hydrazones with p-nitrophenyl moiety were synthesized by solvent-free and conventional synthetic methods with good to excellent yields. The synthesized hydrazones were evaluated for their anti-inflammatory activities using carrageenan-induced paw edema in mice. All the compounds indicated significant anti-inflammatory activity, demonstrating slow onset of action and longer duration of action compared to celecoxi...

Phytochemical and Antimicrobial Studies of Xylopia Aethiopica Stembark Extracts

The preliminary screening of phytochemical constituents of extracts of Xylopia aethiopica was evaluated. The n-hexane extract revealedthe presence of terpenoids, alkaloids, and steroids, while the presence of alkaloids, terpenoids, saponins, steroids, and phenolics was indicated in ethyl acetate extract, and the methanol extract contained tannins, flavonoids, phenolics, terpenoids, saponins, alkaloids, steroids. The medicinal property of the extracts was investigated using in-vitro antimicrob...

Structure-based Discovery of Multi-target Directed Anti-infammatoryp-nitrophenyl Hydrazones; Molecular docking, drug-likeness, in-silicopharmacokinetics, and toxicity studies

We designed novel p-nitrophenyl hydrazones as multi-target inhibitors of COX-2, 5-LOX, and H+/K+ ATPase in a bid to overcome side effects associated to NSAIDs and coxibs. Specifically, compounds 1-(4-nitrophenyl)-2-[(3,4,5-trimethoxyphenyl)methylidene] hydrazine (3), 4-hydroxy-2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]thiochroman-1,1-dioxide (6), 4-methoxy-2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]thiochroman-1,1-dioxide (8), 2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylid...

ASSESSMENT OF THE EFFECTS OF CARBONATED DRINKS ON THE ENAMEL OF THE TEETH

ABSTRACT Assessment of the effects of carbonated drinks on the teeth have been carried out. Five white shelled hard-boiled eggs were placed in clear cups and labelled (Soda Drink, Diet Coke, Coke, Tap Water and Vinegar), with the respective selected liquid poured into the cups and ensured the liquid covers the eggs placed in the cups. The eggs were allowed to sit for 72 hours. At 72 hours the eggs were removed from the cups for inspection. The egg in water showed no changes, this is because t...

Assessment Of Heavy Metal Pollution in Water, Soil and Rice Grown Around River Yobe, Nigeria

ABSTRACT The study was carried out to determine the levels of pollution, by selected metals. in water, soil and rice grown around River Yobe, Nigeria. The samples were collected from four different locations and were analyzed for physicochernical parameters, heavy metals and pollution indices. The pH of water and soil samples were found to be within the range of 6.47 ± 0.05 — 6.85 ± 0.13 and 6.00 — 7.70 respectively. The EC, Alkalinity, chloride, hardness, TDS and turbidity of the water...

The Preparation Of Magensium Glucourantes From Acacia Seyal Var. Seyal Gum

Abstract In this investigation,physicochemical properties of Acacia seyal(Talha) sample was studied [moisture content (10.79%), ash (1.1294%), nitrogen (0.15%), specific optical rotation (+46.1°), pH (4.5)]. Mineral contents of Ca and Mg in two samples (S1gum, S2 magnesium glucurnates and S2) has been analysizedby using Atomic Absorption Spectroscopy (AAS), the results were (Ca in sample S1 = 1934.4, Ca in sample S2 = 65.22, Mg in sample S1 = 19.86 and Mg in sample S2 = 1264.8). List of Co...

Constituents of Celery (Apium graveolens ) Seed Oil and its Biological Activity

Abstract This study was aimed to extract the fixed oil of Apium graveolens through the process of maceration with normal hexane. The oil was analyzed by gas chromatography-mass spectrometry. The antimicrobial activity was also estimated. The GC-MS analysis of the studied oil showed the presence of 45 constituents. Major components are: i) 9-Octadecenoic acid methyl ester (56.04%) ii) 9, 12-Octadecadienoic acid methyl ester (13.47%) iii) Hexadecanoic acid methyl ester(12.05%) iv) Methyl steara...

Characterization of Flavonoids from Albizia Amara Leaves and Their Biological Activity on Microbes

Abstract Phytochemical screening of methanol extract of leaves of Albizia Amara revealed the presence of secondary metabolites: saponins, alkaloids, tannins, glycosides and flavonoids. Powdered shade- dried leaves (1kg) of A. amara. were extracted with 95% ethanol at room temperature for 48 hours, The crude extract was suspended in water and partitioned with organic solvents in order of increasing polarity, petroleum ether, chloroform ethyl acetate and n-butanol, three compounds were isolated...


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