ABSTRACT Phytochemical and proximate analyses were carried out on leafy stem and flower head extract of Centaurea praecox grown in Sokoto, using standard methods. The result of phytochemical analysis shows that the flower head contain 1.67mg/100g Alkaloid, 2.50mg/100 saponins, 5.20mg/100g flavonoid, 4.07mg/100g Steroid. The proximate analyses revealed that the flower head contain 3% moisture, 11.5% Ash, 3% crude lipid, 3.5% crude protein, 25% crude fibre and 57% carbohydrate. The mineral anal...
In Africa traditional studies have shown that herbal medicine proves to be one of the best forms of treatment mensure to preventing or managing a disease condition. Sida coryembosa is a plant gotten from the eastern part of Nigeria Nnewe north to be precise and certain claims and attributes has been said about the plant in wound healing and a possible treatment to peptic ulcer as a result of oxidative stress. The roots, stems and leaves were used for the research. 100grams of each was weighed...
ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the stem bark extract but present in the seed oil extracts. However, the quantitative studies showed that proanthocyanidin, total phenol, total tannins ...
ABSTRACT Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the leaves of Azadirachta indica of Meliaceae family. The extracts were investigated for phytochemical constituents such as tannins, saponins, alkaloid...
ABSTRACT Phytochemical and Proximate analyses of two samples of Aloe vera from variable habitats (highland and lowland) of Sokoto metropolis were accessed. Phytochemical and proximate compositions of highland sample were 8.16mg/100g of Saponin, 3.40mg/100g of Glycoside, 1.80mg/100g of Alkaloid and 2.50mg/100g of Anthraquinone. Proximate constituents’ analysis revealed 6% of Moisture, 10.5% of Ash, 2.5% of Crude lipid, 8.13% of Crude protein, 1% of Crude fibre and 70.57% of Carbohydrate resp...
ABSTRACT Exposure to environmental toxicant was known to cause neuronal disorders in humans. Hence, the present study evaluates the toxic effect of leachate (an environmental toxicant) in the synaptosomes of female rats and the reversal effect of phenolic-rich fraction from Croton zambesicus. Fifty animals were divided into five groups. Group I (Control) received 0.5ml of distilled water only, Group II (non-withdrawal) received 0.5ml of leachate for 14 weeks, Group III (withdrawal) received 0...
TITLE PAGE THE EFFECT OF HYDROALCOHOLIC EXTRACT OF AFRAMOMUM MELEGUETA ON SUPEROXIDE DISMUTASE ACTIVITY IN ALLOXAN INDUCED DIABETIC WISTAR ALBINO RATS BY EBELEME EBENEZER NAU/ 2012474175 SUBMITTED TO THE DEPARTMENT OF APPLIED BIOCHEMISTRY FACULTY OF BIOSCIENCES IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE AWARD OF A BACHELOR OF SCIENCE (B.Sc) DEGREE IN APPLIED BIOCHEMISTRY. NNAMDI AZIKIWE UNIVERSITY, AWKA. AUGUST, 2016 APPROVAL PAGE This is to certify that this research proje...
TABLES OF CONTENT TITLE PAGE i CERTIFICATION ii DEDICATION iii ACKNOWLEDGEMENT IV TABLES OF CONTENT V ABSTRACT VI CHAPTER ONE 1.0 INTRODUCTION 1.1 LITERATURE REVIEW 1.2 THE LIVER 1.2.1 CARBON TETRACHLORIDE 1.3.0 LIVER FUNCTION TEST 1.3.1 TOTAL CHOLESTEROL 1.3.6 FUNCTIONS OF THE LIVER 1.6.0 LIPID PEROXIDATION 1.8.2 BOTANICAL DESCRIPTION OF DENNETIA TRIPETALA 1.8.3 COMMERCIAL / ECONOMIC IMPORTANCE OF DENNETTIA TRIPETALA 1.8.4 PHYTOCHEMICAL CONSTITUENTS OF DENNETTIA TRIPETALA 1.8.4.1 P...
Effect of Chrysophyllum albidum pulp varieties on biochemical parameters was investigated using albino rat model. Thirty male Albino rats were divided into five groups of six rats each. A group served as the control while four groups served as the test groups A, B, C and D. Test groups A and B were placed on 5% and 25% respectively compounded feed of sweet Chrysophyllum albidum pulp variety while test groups C and D were respectively placed on 5% and 25% compounded feed of sour Chrysophyllu...
The class of β-lactam antibiotics has antibiotic agents that possess β-lactam ring as part of their molecular structure, these agents includes cephalosporins, monobactams, penicillins and carbapenems. these are the most widely used antibiotics which act by inhibiting the synthesis of the bacterial cell wall such activity leads to the lysis and death of the bacteria. due to the wide applications of these antibiotics bacteria have developed resistance mechanism against these antibiotics...
The goitrogenic potential of a plant or food depends upon the amount of active goitrogen present in it. Various procedures like soaking, washing, boiling and cooking can help in reducing the goitrogenic potency of these foods. These, along with the intake of iodide supplements are generally practiced in areas where goitrogenic foods are routinely consumed. In this experiment, goitrogenic contents of some commonly consumed vegetables were assayed and analysed.
The folding protein (and protein folder) is beset with a number of problems in translating the simple instructions encoded by DNA into the complex, three-dimensional structure of a correctly folded protein. Nature has solved these problems in an adequate, if not elegant, fashion, but we are just beginning to understand the variety of strategies that cells use to ensure efficient protein folding. This minireview will focus on several of the more general principles of assisted folding using the...
Extracts of J. gossypifolia L. have been reported to have several medicinal values, including potential anti-cancer and anti-inflammatory properties. In this study, we investigated the anti-clastogenic and hepatoprotective, effects of the ethanolic leaf extract of J. gossypifolia L. in potassium bromate (KBrO3)-induced toxicity in rats. The general trend of the results indicates significant increases (p
We evaluated the brain, lung, and heart oxidative stress in rats exposed to aerosol of an over-thecounter pyrethroid insecticide product in Nigeria. The experimental animals were randomly divided into four groups: group I (control) was not exposed to the insecticide aerosol, while groups II, III, and IV were exposed to 6.0 mL m-3, 12.0 mL m-3, and 18 mL m-3 of insecticide ae...
Background: The current upsurge in the use of polyherbal remedies and coupled with loose regulation on public access to these products underscore research efforts to evaluate their biochemical effect, noting also that many of the polyherbal medicines lack scientific evidence to support their medicinal claims. Objective: We therefore investigated the potential genotoxicity, hematotoxicity and ...