Abstract: The inhibitory effects of Momordica charantia linn, Isoberlinia doka, Terminalia avicennioides, Tamarindus indica and Crotalaria retusa L aqueous leaves extracts on Opisthacanthus capensis (Black creeping scorpion) venom phospholipase A2 (PLA2 ) activity was investigated. The enzyme from O. capensis venom had a pH and temperature optima of 5 and 60˚C respectively with an activation energy of 5.20 Kcal/mol. Different concentrations (4mg, 6mg and 8mg/ml) of Isoberlinia doka and M...
The introduction of combined therapy has been an important breakthrough in the treatment of HIV infection, however for proper eradication, HIV pathogenesis has to be understood. Despite treatment with combinatorial therapies, a functional cure approach would be very effective in suppressing viraemic load in the host to such low levels that the immune system would be able to control the infection without the need for antiretroviral therapy, neither inflicting harm upon the host nor transmissio...
To test the effect of Nauclea latifolia fruit on a diabetic rats. This was meant to see if the fruit has the ability to reduce blood sugar level.
The work was aimed at investigating the effect of Cocus nucifera on male albino rats. A number of rats were placed in groups and all groups were fed Cocus nucifera except one group, the control group. Analysis of results was done with ANOVA.
Alpha-amylases are starch degrading enzymes and their activities have been found to be the major change that occurs in the ripening of bananas and plantains. This study was designed to basically develop a simple spectrophotometric method to monitor some of the biochemical processes involved in the ripening of Giant horned plantain (Apantu), French horned plantain (Apem) and local banana (Abibifo mpua).The pericarp from five ripening stages was collected and alpha amylases were extracted with ...
Abstract The effect of Shea butter rich diet on gentamicin induced nephrotoxicity in rats was determined. Thirty (30) male and female albino rats grouped into 6 (normal, negative, positive, 10%, 20% and 30% Shea butter rich diet groups respectively) of 5 rats each were used for the study. Phytochemical analysis was carried out on the Shea butter used for this study which revealed the presence of saponin, tannin, alkaloid, terpenoid, flavonoid, and reducing sugar, while coumarin was absent. ...
Abstract: Phytoremediation has been identified as an effective option for the clean-up of petroleum hydrocarbon contaminated soil. The aim of this study is to assess the potential of Vigna unguiculata L. Walp (cowpea) in the remediation of used motor oil contaminated soil. The germination and growth of cowpea on soil contaminated with 5% (w/w) of used motor oil was monitored for 28 days. One of the treatments received 15% (w/w) poultry manure seven days after pollution. Result of the phys...
ABSTRACT Comparative assessment of the phytochemical content and antioxidant potential of Azadirachta indica (neem) and Parquetina nigrescens (bullock) is the aim of this study. In order to achieve this, both plants were harvested from the botanical garden, University of Ibadan. The leaves were removed from the stem, washed with running water to remove contaminants, oven dried at 37˚C and milled into powder. The qualitative analyses of both plants were investigated after which six selected p...
ABSTRACT The metabolism of Paracetamol has been studied in Isoniazid pretreated albino rats and compared with control. During this study, thirty-five (35) laboratory albino rats were used divided into five (5) groups of seven (7) rats each. Group I served as control and the rats were only administered with 120mg/5ml/kg body weight dose of Paracetamol interperitoneally. However, Groups II-V served as test groups and the members were pretreated with 10mg/kg body weight dose of Isoniazid interpe...
Citrullus lanatus is medicinal plants believed to have many agents acting in different ways for the health benefits of human. This study investigated the acute phytochemical contents and effect of the methanol extract on weight changes, relative organ weight, hematological parameters and biomarkers of prostate dysfunction. The result indicated the presence of alkaloids, terpenes, flavonoids, Reducing sugar, tannins and phenols. Acute toxicity studies showed that the extract was safe at 5000mg...
Abstract Soft drinks are consumed daily in Nigeria due to their characteristic taste, palatability, affordability and thirst quenching potential. This study quantifies the amount of electrolytes of Biochemical significance in selected soft drinks sold in Port Harcourt and their pH values. The samples included six frequently consumed soft drinks; (Coke, Sprite, Fayrouz, Mountain-Dew, Fanta and Pepsi). The results showed that the samples contain relatively high amount of Sodium(Na+) ranging fro...
ABSTRACT The high cost of treated water makes most people in the rural communities to resort to water sources which are normally of low quality and which expose them to waterborne diseases. The main objective of this work is to evaluate the effectiveness of Cucurbita pepo seed powders for the removal of turbidity in river water using Alum as a standard. Water samples were co...
ABSTRACT. A study of haemoglobinopathies in Ehime-Mbano Local Government Area of Imo State was carried out with mostly students of secondary schools in the area who are true representatives of the population. The result showed that 20% of the people randomly sampled are carriers of the sickle trait (HbAS) while the remaining 80% have genotype of HbAA. The incidence of blood group antigen showed that 29.2% (146), 12.0% (60), 3.0% (15) and 55.8% (279) have antigens A, B, AB and O respectively. ...
Students industrial work experience scheme SIWES is a skill learning programme designed to expose and prepare students of engineering, technology, environmental sciences, medical sciences, pure and applied sciences for the industrial work situation which they are likely to meet after graduation. Duration for SIWES is a six months programme for universities, four months for polytechnics end of ND 1, four months for colleges of Education end of NCE II. The students industrial work experience ...
Introduction Epilepsy is a common medical and social disorder or group of disorders with unique characteristics. Epilepsy is usually defined as a tendency to recurrent seizures. The word “epilepsy” is derived from Latin and Greek words for “seizure” or “to seize upon”. This implies that epilepsy is an ancient disorder; indeed, in all civilizations it can be traced as far back as medical records exist. In fact, epilepsy is a disorder that can occur in all mammalian species, probabl...