Abstract Pediatric CRC has a poor prognosis compared with adult CRC mainly due to delayed diagnosis. *us, early diagnosis based on a high degree of suspicion could be the most important factor in a more favorable prognosis, especially in patients with predisposing factors. CRC is one of the major causes of cancer-related death globally [1, 2]. *e most common histological subtype of CRC is adenocarcinoma NOS, of which mucinous adenocarcinoma is a distinct subtype and is characterized by abunda...
ABSTRACT Sexually Transmitted Infections (STIs) are infections passed from one person to another during sexual contact though some are also passed from mother to child during pregnancy, birth or while breast feeding. STIs constitute an important public health problem. The early detection and treatment of STIs are important aspects of a comprehensive approach to reducing the spread of HIV. Although public-sector services are available even in the most resource-poor countries, they are not acce...
ABSTRACT BACKGROUND Severe anaemia is prevalent in most African countries and is highly associated with increased morbidity and mortality in under-fives. Globally, iron deficiency is responsible for half of all anaemia, In Africa causes like malaria, hookworm and other helminths, other nutritional deficiencies, chronic infections and genetic conditions prevail and these causes differ from place to place. Exhaustive diagnostic evaluation is needed to establish causes of severe anaemia however...
ABSTRACT Background: A worldwide estimated annual case of cervical cancer is 528,000 and ends with 266,000 annual deaths. In developing countries, it accounts for about 85% for both morbidity and mortality. In sub-Saharan Africa the incidence is 25.2%, mortality 23.2% and five-year prevalence is 27.6%. In Tanzania the rate of cervical cancer is 54.4% per 100,000 people a year. This indicates that, cervical cancer is a public health concern in Tanzania. Objective: assessing clinical profile a...
ABSTRACT Background: Benign prostate hypertrophy (BPH) is a prostatic enlargement associated with the presence of voiding symptoms and/or histological evidence of hyperplasia on biopsy. Transurethral resection of the prostate (TURP) is considered the gold standard management for BPH. Despite being one of the common urological procedures in Tanzania, complications of TURP have not been well explored. There was limited published information on the incidence and prevalence of Benign Prostate Hy...
ABSTRACT BACKGROUND: Escherichia coli (E. coli) is a bacterium that can asymptomatically colonize a woman’s vagina and up to 31% of pregnant women are colonized worldwide. Furthermore, vaginal colonization with E. coli is associated with adverse pregnancy outcomes, such as preterm birth and stillbirth. It is also associated with neonatal sepsis or meningitis when transmitted to the foetus through amniotic fluid or to the neonate during delivery. To date in Namibia data on the colonization a...
ABSTRACT Background Surgical site infection (SSI) is one of the common complications after cesarean section in Tanzania and other parts of the world. High rates of SSI have been reported in literature with demonstrable multiple drug resistance of the isolates. Identification of isolates and their susceptibility pattern is key to development of evidence-based treatment protocols and effective preventive strategies. Objectives: The aim of this study was to determine the bacterial etiology, ant...
ABSTRACT Background: Nasopharyngeal carcinoma (NPC) is an uncommon malignant tumor which has been reported invariably and cases have been encountered in Tanzania. Though rare they are associated with potential morbidity and mortality. The aim of this study was to characterize the clinico-pathological profile of such neoplasm in our set up. Methods: A retrospective review of 25 cases from hospital archives for 3 consecutive years was done where all patients with a histopathologically confirme...
ABSTRACT Aims: The aims of the current study were to determine the prevalence of epidermal growth factor (EGFR) receptor in patients diagnosed with esophageal squamous cell carcinoma (ESCC) as well as assessing the correlation of overexpression of EGFR with age, gender and tumor grades of the cases. Study Design: This was a cross-sectional analytical study.
ABSTRACT Background: Severe Acute Malnutrition is a major public health concern and the leading cause of death among children under five years. Therefore, this study was done to determine the prevalence and predictors of bacteraemia among children with Severe Acute Malnutrition aged 6 to 59 months admitted at Dodoma Regional Referral Hospital. Methods: This was a hospital based, analytical, cross section study conducted from January to June 2020. All children aged 6 to 59 months admitted at ...