Abstract Study Objective(s): The main study objective was to report on surveillance data from, assess the preparedness and challenges of home-based care for COVID-19 patients and hhealth workers in four Counties (Kakamega, Vihiga, Bungoma, Busia) in Kenya. Design, setting and Participants: The study design and setting used was both qualitative and quantitative and it involved random sampling and snowballing sampling, to obtain data from health workers and patients in Home-Based Isolation. Pa...
Abstract Introduction: in Kenya, about 1.5 million people are living with the Human Immunodeficiency Virus (HIV). Antiretroviral therapy aids in viral suppression. However, drug-resistance threaten the gains of the HIV infection control program. To determine the prevalence of HIV-1 drug-resistant mutations among adults on ARV therapy attending Khunyangu sub-county hospital in Busia County, Kenya, 50 blood samples were analyzed. Methods: the samples were collected from November 2019 to Janua...
Abstract Introduction: mutations are important by ensuring that the HIV-1 agent remains fit in the environment and evades drugs that are developed purposely to kill them. In Kenya, mutations conferring resistance to available ARVs have been reported in previous studies. However, there is a paucity of information on whether these previous studies have reported all mutations conclusively that confer resistance to available drugs leading to virologic failure. Therefore, this study was sought to...
Abstract The healthcare sector has undergone significant changes within the past decades, and amidst these changes, attaining efficient and effective healthcare service delivery has remained a distant prospect. This study, therefore, sought to find out the effect of supply chain information systems on service delivery in the public health care sector in the county governments of the western region. The study was anchored on the theory of human service delivery and health network metrics. The...
Abstract Background: The capacity of healthcare providers to execute an accurate initial assessment is crucial for recognizing the urgency and treatment needs of patients and for creating baseline data from which any changes in patient status may be monitored. In Western Kenya, there is little evidence of studies carried out on the competence of healthcare providers in the clinical management of myocardial infractions thus this study's main aim was to investigate the competence of healthcare...
Abstract Healthcare organisations are in dire need of a culture in which nursing employees are dedicated, motivated, and strongly associated with their sacred profession. This calls for strengthening the quality of the work life of nurses, which is an antecedent of organisational commitment. However, a number of studies that have explored the relationship between quality of work life and organisational commitment as moderated by organisational culture have been conducted in western countries...
Abstract ackground. Albizia coriaria Welw ex. Oliver (Fabaceae) is one of the plants used by herbalists in the East Africa community to prepare herbal remedies for the management of symptoms of TB. Despite its widespread use, the antimycobacterial activity of this plant was uninvestigated and there was contradicting information regarding its cytotoxicity. Methods. Cytotoxicity (MTT), antimycobacterial activity (MABA), and phytochemical screening were conducted on crude extracts (hexane, chlo...
Abstract Background: Whereas the efficacy of Entada abyssinica (fabaceae) extracts against various ailments has been scientifically validated, its safety has not been established. This study was undertaken to evaluate the toxicity effects of methanolic stem bark extract of E. abyssinica on biochemical, haematological and histological parameters of Wistar albino rats following repeated oral administration. Methods: Wistar albino rats of both sexes were randomized into groups and orally admini...
Abstract Background. Many studies have been undertaken on the medicinal values of Erythrina abyssinica Lam. ex DC. (Fabaceae). The details, however, are highly fragmented in different journals, libraries, and other publication media. This study was therefore conducted to provide a comprehensive report on its ethnobotany, ethnomedicinal uses, phytochemicals, and the available pharmacological evidence supporting its efficacy and safety in traditional medicine. Method. We collected data using a...
Abstract ervical cancer is still a major health risk for women even though it is preventable. Its prevalence indicates lack of success with screening and early diagnosis. Considering most women who visit hospitals have advanced stages of the disease, deaths from this type of cancer will rise if immediate action is not taken. This study sought to determine the obstacles to interpersonal communication as a means for encouraging adoption of cervical cancer testing in Uasin Gishu County, Kenya. ...
Abstract Malaria and malnutrition remain primary causes of morbidity and mortality among children younger than 5 years in Africa. Studies investigating the association between malnutrition and subsequent malaria outcomes are inconsistent. We studied the effects of malnutrition on incidence and prevalence of malaria parasitemia in data from a cohort studied in the 1990s. Data came from the Asembo Bay cohort study, which collected malaria and health information on children from 1992 to 1996 in...
Abstract Background: In Kenya, the increased use of motorcycles for transport has led to increased morbidity, mortality, and disability. These injuries exert a burden on the public health system, yet little information exists on health care resource usage by motorcycle crash injury patients. We aimed to estimate the burden of motorcycle crash injuries on the health system in Kisumu City. Methods: We conducted a 6-month prospective study of all motorcycle crash injury patients who presented t...
Abstract Introduction: Strong health systems are essential platforms for accessible, quality health services, and population health and attainment of the Sustainable Development Goal (SDGs). Descriptive methods have been used to assess the health systems strength and impact, however, there is inadequate knowledge on methods of analyzing huge number of indices to provide systematic evidence that service readiness is improving or deteriorating over time. Methods: We utilized data from a cross ...
Abstract Background: Anaemia is a major cause of morbidity and mortality among people living with human immunodeficiency virus (HIV) infection. While adherence to antiretroviral treatment (ART) reduces the incidence of anaemia, non-adherence (defaulting) to ART is associated with a number of haematologic derangements including anaemia. However, the mechanisms and predictors of anaemia have not been examined among ART defaulters in western Kenya. This study, therefore, aimed at evaluating the...
Abstract Background: The burden of HIV and malaria co-infection lies disproportionately in the Sub-Saharan Africa region which bears most of the malaria endemic zones. While both malaria and HIV are known to dysregulate hepatic and renal functions, the combined effect of co-infection with malaria and HIV on hepatic and renal function among children remains poorly characterized. Objective: To assess liver and renal functions in HIV-malaria co-infected children in Western Kenya. Methods: A cro...