Medical & Health Sciences

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Research Papers/Topics Medical & Health Sciences

NUTRITIONAL EFFECT ON DRUG SENSITIVITY IN MALARIA USING CHLOROQUINE-SENSITIVE Plasmodium berghei- INFECTED MICE

ABSTRACT Malaria  is  entirely  preventable  and  treatable  vector-borne  disease  which  account  for  an estimated 219 million cases globally, killing about 660,000 people, mostly children under five years of  age. The synergistic effects of nutrition in malaria infection were observed in mice fed with different nutrients (protein, carbohydrate, and grower mash) compounded diets for eight weeks prior to infection. All the experimental mice were infected with plasmodium berghei....

EFFECT OF D-RIBOSE- L-CYSTEINE ON REDOX BALANCE AND INFLAMMATION IN PARADOXICAL SLEEP-DEPRIVED PREGNANT RATS

TABLE OF CONTENTS TITLE PAGE CERTIFICATION DEDICATION ACKNOWLEDGEMENT TABLE OF CONTENT LIST OF TABLES LIST OF FIGURES ABSTRACT CHAPTER ONE   INTRODUCTION​​​​​​​​​​1 1.1 AIM OF THESTUDY​​​​​​​​​2 1.2 OBJECTIVES OF THESTUDY​​​​​​​​2 1.3 LIST OF ABBREVIATIONS​​​​​​​​3 CHAPTER TWO: LITERATURE REVIEW 2.1 STRESS​​​​​​​​​​​4 ​2.1.1 TYPES OF STRESSORS​​​​​​​5 2.1.2 EFFECTS OF OXIDAT...

Cytological Findings in Urine of Adult Residents of Urinary Schistosomiasis Endemic Community in Cross River State, Nigeria

Aims:  To investigate urinary cytological abnormalities among adult residents of a urinary schistosomiasis endemic community.   Study Design:  Ethical approval, consent from the village Head/villagers, parasitological survey and cytological analysis of urine.   Place and Duration of Study: Adim Community in Cross River State, Nigeria between May and November 2014  Methodology: Urine samples from 160 sex matched adults aged 18–85 years were examined  u...

Knowledge of, Perception of, and Attitude towards Uterine Fibroids among Women with Fibroids in Lagos, Nigeria

Objectives. The study was to assess the level of knowledge of, perception of, and attitude towards uterine fibroids among women diagnosed with the condition. Methods. It is a cross-sectional descriptive study carried out among women diagnosed as having uterine fibroids in two gynaecological clinics in Lagos, Nigeria. Eligible women were recruited and a structured interviewer-administered questionnaire was used to collect the required information. Statistical analysis of data was done using...

Cariostatic effect of conventional GIC versus composite resin [October 10, 2018]

Search result: Eight clinical studies to topics concerning orthodontic bonding, root- and tooth restorations were found. Clinical outcomes: The results indicate a higher cariostatic effect of GIC for orthodontic bonding and tooth restorations in permanent teeth. No difference was found for tooth restorations in primary teeth when compared to fluoride containing composite and root restorations. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic sear...

Coating of high-viscosity GIC [October 09, 2018]

Search result: Three prospective clinical controlled trials were found. Clinical outcomes: The results indicate that there may be a trend that coating can protect Fuji IX GP Extra against wear. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity...

Cariostatic effect of conventional GIC versus compomers [October 09, 2018]

Search result: Five clinical trials were found and traced. Clinical outcomes: The results are conflicting or suggest no difference between conventional GIC and Compomers in regard to their anticariogenic effects after 3-4 years. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessmen...

Cariostatic effect of resin-modified GIC (RM-GIC) versus compomers [October 08, 2018]

Search result: Twelve clinical trials were found and traced. Clinical outcomes: The overall results suggest no difference between RM-GIC and Compomers in regard to their anticariogenic effects. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validit...

Antibacterial effect of GIC versus composite resin [October 08, 2018]

Search result: One clinical trial was found and traced concerning resin-modified GIC (RM-GIC). Clinical outcomes: The material was Fuji II LC (compared to: Tetric Flow and Helioseal F). No trials were identified comparing conventional GIC (C-GIC) with composite resin. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of datab...

Do patients, who have received polytetrafluoroethylene (PTFE) based sutures experience less, similar or more gingival inflammation than patients with polyamid (nylon) based sutures? [June 05,

Search result: No direct clinical data to the topic could be found. Clinical outcomes: However, one systematic review reported that ePTFE sutures cause clinically less inflammation than silk sutures in humans. One animal study (in rabbits) found less general inflammation from ePTFE sutures than Nylon sutures. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evid...

What is the clinical bleaching effect of 10 and 15% Carbamide peroxide based products for home use tooth whitening? [November 29, 2017]

Search result: One systematic review and 7 clinical trials were found. Clinical outcomes: The results suggest Carbamide peroxide (CP 10 and 20%) to be more effective in color change than Hydrogen peroxide (HP). In addition, (i) CP 10% appears no more effective than CP 5%, (ii) no difference was observed between CP 10% and CP 15% and (iii) the use of CP 10% appears more comfortable to patients than HP 10%. However, its clinical relevance is unfavourable and potential side-effects of at-home...

What is the clinical merit of bioactive glass in restorative dentistry? [November 28, 2017]

Search result: One systematic review was found. Clinical outcomes: The limited results suggest that bioactive glass may be effective in remineralising dentin. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace...

What are the clinical merits of CAD/CAM manufactured dentures? [November 27, 2017]

Search result: Two older systematic reviews (until June 2012) and one recent clinical trial (2016) were found. Clinical outcomes: The results suggest that CAD/CAM post-sintered denture frameworks are superior to CAM pre-sintered denture frameworks and that CAD/CAM systems may show less marginal discrepancy than conventional methods for framework fabrication.. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and ...

How do Composite (CAD/CAM) crowns compare to ceramic crowns in terms of clinical restoration survival? [November 26, 2017]

Search result: One clinical trial was found. Clinical outcomes: The results suggest that Composite (CAD/CAM) crowns are inferior to ceramic crowns after 3 years. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not repl...

How do Fibre posts compare to Metal posts in terms of clinical restoration survival? [November 25, 2017]

Search result: Two systematic reviews and two additional trial reports that were not covered by the systematic reviews were found. Clinical outcomes: The older systematic review (2005) included only one relevant trial not included in the other more recent systematic review (2014) and stated higher failure risk for metal-posts. However, the more recent systematic review included 14 trials and found no significant differences. In addition, one trial indicated higher fracture risk and lower ...


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