Abstract Introduction Point-of-care molecular diagnostics offer solutions to the limited diagnostic availability and accessibility in resource-limited settings. During the COVID-19 pandemic, molecular diagnostics became essential tools for accurate detection and monitoring of SARS-CoV-2. The unprecedented demand for molecular diagnostics presented challenges and catalyzed innovations which may provide lessons for the future selection of point-of-care molecular diagnostics. Areas Covered We s...
Abstract/Overview Annually, 125.2 million pregnant women worldwide risk contracting malaria, including 30.3 million and 1.5 million in Sub-Saharan Africa and Kenya respectively. At least three doses of sulphadoxine pyrimethamine for intermittent preventive treatment of malaria in pregnancy (IPTp-SP) is recommended for optimal benefit. Kenya recorded low IPTp-SP optimal uptake in 2015. This study investigated the prevalence of and factors influencing IPTp-SP optimal uptake in Sabatia Sub C...
Abstract/Overview Globally, the proportions of women of reproductive age living with HIV vary between regions, with significantly higher proportions in sub-Saharan Africa. The scale-up of multiple-drug antiretroviral therapy in Africa has changed childbearing dynamics for HIV-positive women, with an impact on pregnancy incidence, although there is little understanding of the factors associated with pregnancy incidence among these women. This descriptive cross-sectional study investigated ...
Abstract/Overview Breast self-examination (BSE) is a simple, low-cost, and non-invasive method that women use to detect breast cancer at early stages. BSE is recommended for teenage and adult women as it helps to detect unusual swelling and lumps. The early intervention reduces the spread of cancer cells and improves health outcomes. This study assessed the knowledge and practices of BSE for early detection of breast cancer among women attending maternal health clinic at Jaramogi Oginga T...
Abstract/Overview HIV-1 genetic diversity results into the development of widespread drug-resistant mutations (DRMs) for the first-line retroviral therapy. Nevertheless, few studies have investigated the relationship between DRMs and HIV-1 subtypes among HIV-positive injecting drug users (IDUs). This study therefore determined the association between HIV-1 genotypes and DRMs among the 200 IDUs. Stanford HIV Drug Resistance Database was used to interpret DRMs. The five HIV-1 genotypes circ...
Abstract/Overview One-third of people with pre-diabetic condition progress to type 2 diabetes within five years. However, with adequate knowledge on diabetes risk reduction behaviors, progression to diabetes can be controlled. We therefore recruited 220 suspected cases of pre-diabetic patients at Busia County Referral Hospital assessed their knowledge, and adaption of risk reduction behavior. A cross-sectional study design and a systematic sampling approach were used. The findings show th...
Abstract/Overview Preconception care involves the provision of health interventions to women and couples before conception and aims at improving their health status, reducing behaviors, individual and environmental factors that contribute to poor maternal and child health outcomes. It has potential to further reduce global maternal and child mortality and morbidity, especially in low-income countries where the highest burden of pregnancy-related deaths and disability occurs. Most often, p...
Abstract/Overview Preconception care involves the provision of health interventions to women and couples before conception and aims at improving their health status, reducing behaviors, individual and environmental factors that contribute to poor maternal and child health outcomes. It has potential to further reduce global maternal and child mortality and morbidity, especially in low-income countries where the highest burden of pregnancy-related deaths and disability occurs. Most often, p...
Abstract Supply chain management is a crucial activity that entails overseeing the movement of materials from the source, throughput, to the end consumer. However, in this endeavour, there are increased instances of uncertainties, i.e., speeds of delivery, flexibility, and environmental factors that affect the services rendered to the end consumer. This drives the concept of supply chain resilience as the ability of an organization to cope with stress from any factors in its environment and ...
Abstract Background: Malaria is the leading cause of mortality in sub-Saharan Africa. Objective: The study assessed the effect of socio-economic factors on high malaria prevalence in a peri-urban setting in Vihiga County, Western Kenya highlands aimed at strengthening implementation of cost-effective malaria control strategies at household level. Method: A longitudinal study was carried out in the study area from December 2019 to November 2020. From patients who presented themselves at Mba...
Abstract Supply Chain Management is a crucial activity that entails overseeing the movement of materials form the source, throughput, to the end consumer. However, in this endeavour, there are increased instances of uncertainties i.e. speeds of delivery, flexibility and environmental factors that affect the services rendered to the end consumer. This drives the concept of supply chain agility which focuses on the speeds of response to any changes in the consumer demands. The healthcare secto...
Abstract/Overview Maternal and neonatal morbidity and mortality are major public health concerns in most developing countries and in under resourced settings. Provision of safe motherhood is of utmost importance in the reduction of maternal mortality. Increasing the proportion of babies that are delivered in health facilities is an important factor in reducing the health risks to both the mother and the baby. This study explored maternal healthcare choices of expectant mothers in Lunga Lu...
Abstract/Overview Health Related Quality of Life (HRQoL) is an important health outcome in the holistic management of patients especially those suffering from life limiting conditions such as cervical cancer. In Kenya, Cervical cancer is the most frequent cancer among women. However, little is known and documented on HRQoL of cervical cancer patients. This study assessed HRQoL of cervical cancer patients in western Kenya. A cross-sectional study involving 334 cervical cancer patients was ...
Abstract Purpose: The post-pandemic management of COVID-19 infections and any emergent outbreaks is because this endemic disease remains a public health concern. Vaccine hesitancy may continue to hamper efforts to respond to any new disease outbreaks and future epidemics. This qualitative study aimed to explore the factors influencing COVID-19 vaccine acceptance and hesitancy in Kenya to gain deeper insights into this issue. Methods: This study was implemented in western Kenya using key info...
Abstract/Overview Maternal and neonatal morbidity and mortality are major public health concerns in most developing countries and in under resourced settings. Provision of safe motherhood is of utmost importance in the reduction of maternal mortality. Increasing the proportion of babies that are delivered in health facilities is an important factor in reducing the health risks to both the mother and the baby. This study explored maternal healthcare choices of expectant mothers in Lunga Lu...