ABSTRACT N-a-tosyl-L-lysyl-chloromethyl ketone (TLCK) has been coupled to ara-C or colchicine encapsulated liposomes via glutaraldehyde treated liposomal phosphatidylethanolamine (Lp-G-TLCK) or sodium metaperiodate oxidized oligosaccharide side chain of liposomal digoxin (Lp-D-TLCK). TLCK has been shown to react with specific histidine residue at the active site of such protein as trypsin and has high binding affinity for simian virus 40 and polyoma virus transformed fibroblasts. A 20-minute ...
ABSTRACT The main objective of this study was to compare the similarities and differences in MRbased and pseudo CT µ-map generation in PET/MR and radiotherapy respectively. The study sought to look at ways attenuation correction could be done on PET hybrid imaging systems and compare them in various ways so as to improve treatment and patient care. The methodology involved patient selection, image processing and generation of both µmaps for PET-attenuation correction and pseudo CT for radio...
ABSTRACT Coastal areas around the world are being shaped by natural and anthropogenic activities. These factors include ocean level rise, tides, geomorphology of the coastline, sand mining and coastal population increase. This study assessed the rate and extent of coastal erosion from 1986 to 2016 of the Teshie coastline; the socio-economic and cultural patterns (causes and effects) and the adaptive strategies undertaken by the locals of Teshie. Analyses of the shoreline change were computed ...
ABSTRACT The thrust o f this study w as to identify the factors w hich influence accessibility and utilization o f health care facilities in the D angm e W est D istrict, and to find solutions to problem s w hich w ere identified. The study covered nine fully operational health centres and health posts in the district, as well as random ly sam pled service providers such as nurses, personnel o f N G O s. heads o f som e governm ent departm ents, opinion leaders and the district director of he...
ABSTRACT Wave and wind dynamics are important in the estimation of beach erosion rates and sediment transport modelling. They are also important in modelling sea fatigue, oil spill transport and planning of coastal and marine activities. This work sought to quantify the magnitude of wave and wind parameters along the coast of Ghana as well as identify how these parameters varied across the year. A nine years wave and wind data from the National Oceanic and Atmospheric Administration (NOAA) gl...
Abstract Ceiba pentandra, Colagigantea,Lanneawelwitschii,Militia excelsa (all non-leguminous) and Milletia zechiana (leguminous) are among the various tree species retained on cropping fields in the Akuapem District of Ghana, but little is known of the actual contribution of these species to soil fertility improvement. Leaf litter samples from the above-mentioned non-leguminous species were analysed to determine their nutrient content. Leaf litter production was also quantified monthly over a...
ABSTRACT This study describes and identifies palynomorphs (spore/pollen and dinoflagellates) from different levels of the CTP-1 well succession in the offshore Tano Basin in order to establish palynostratigraphy of the studied sediments. The palynomorphs are used as an age tool for the sediments after comparison with other species or sediments reported from other parts of the world, especially the North Gondwana Province (ASA) region. Sedimentary Organic Matter is used to establish palynofaci...
ABSTRACT A total of 484 children aged between 1 -10 years who reported at the emergency unit of the Department of Child Health, Korle Bu Teaching Hospital with clinical malaria were recruited for this study. The children were categorized into four main groups of clinical malaria namely, severe malaria anaemia (SA), cerebral malaria (CM), uncomplicated malaria (UM) and intravascular haemolysis, or bloody urine (IVH). The aim of the study was to determine the role of complement activation in th...
ABSTRACT In this study, the effective dose and its associated cancer risk were estimated for adult patients undergoing the five most common types of CT examinations (head, neck, chest, abdomen and pelvis) at Sweden Ghana Medical Centre (SGMC) in the Greater Accra Region of Ghana. Two main methods were employed in the study: patients’ data collection and phantom measurement to verify the patient data. The effective doses were estimated using the dose length product (DLP) from the control con...
ABSTRACT The suitability o f five Schistosoma genus-specific monoclonal antibodies (MoAbs) (Sh3/34.10, Sh3/38.2, Sh4/14.3, Sh5/32.30 and Sh5/34.10) in detecting schistosome antigens in infected human and cattle was evaluated. These antibodies were employed in various diagnostic assays to diagnose human and animal schistosomiasis. Extant MoAb secreting hybridoma cells were first propagated in culture to produce the MoAbs. The culture supernatants containing secreted antibodies were analysed by...
ABSTRACT It is generally acknowledged that availability of data remains critical to effective monitoring of poverty indicators and evaluation of policies and programmes towards alleviating poverty. The paucity of data has reduced the frequency of measuring poverty indicators at the national and regional level. District level poverty indicators are yet to be estimated since sampling designed data collected can only provide national and regional level indicators. This thesis applied multiple im...
ABSTRACT Like the developing and developed countries in the world, Bayelsa State has also embraced and is involved in the processing of various aspects of e-government, particularly in its ministries, agencies and departments.The study is based on jugdemental methodology in using to solve the thesis problem,whose objectives are to know the main obstacles in implementing e-government in Bayelsa State, to know which obstacle have the most effect in implementing e-government in Bayelsa State, ...
ABSTRACT The ameliorative potential of Psidium guajava leaf ethanol extract on Paraquat induced toxicity and oxidative stress in Albino Rats were investigated. Thirty (30) healthy male wistar rats were divided into five groups of six animals each. Group 1 served as the normal control (NC) and received normal saline, Group 2 (Intoxicated control) received 3.5mg/kg of paraquat. Group 3 (PG200) received 200mg/kg PG leaf extract + 3.5mg/kg PQ, Group 4 (PG400) received 400mg/kg PG leaf extract +...
ABSTRACT A study was made of the effect on pepper quality of the traditional method of processing the "Balancotta" variety of Piper nigrum (black pepper). The study comparatively considered the microbiological quality, drying method, drying rate, colour and appearance, washing or cleaning method, prior to fermentation or heaping as well as an alternative method - heat treatment processing of the commodity. Using a solar dryer as a drying apparatus resulted in 9.8% moisture content of the sam...
ABSTRACT The use of raw maize cob (rmc) and activated maize cob (amc) as a low-cost natural adsorbent for the removal of Pb2+ and Cu2+ ions from simulated waste water was studied. Batch experiments were conducted to determine the effects of varying contact time, initial metal ion concentration, adsorbent dosage, pH and temperature of adsorption on adsorption equilibrium quantity (qe ) and percentage removal (% R). % R increased with increasing adsorbent dosage for the two metal ions. It also...