ABSTRACT The CysF9[93]β sulphydryl group is an indicator for tertiary and quaternary structure change in haemoglobin. Allosteric effectors such as proton and inositol hexakisphosphate (inositol-P6) influence its reactivity. This work was undertaken to study the effects of inositol-P6 and pH on the kinetics and equilibrium of the reaction of CysF9[93]β of dog (Canis familiaris) and donkey (Equus asinus) haemoglobins with 5,5'-dithiobis(2-nitrobenzoate) (DTNB). The number of sulphydryl groups...
ABSTRACT Potable water supply in Ado-Ekiti is inadequate resulting in increased demand for groundwater in the metropolis. Geologically, Ado-Ekiti is underlain by hydrogeologically challenging crystalline basement rocks whose hydraulic properties are characterised by extreme variations over short distances. Prospective groundwater zones are poorly defined in the hard rock terrain. A thorough and definitive evaluation of the overall groundwater resource in such terrain is imperative. This study...
Abstract In the Ibokun area of the Ilesha schist belt of southwestern Nigeria, the dominant rock types are granite gniess and amphibolite. The granite gneiss is medium to coarse grained, with lineation marked by alignment of biotite and microcline porphyroblasts. The amphibolite is commonly massive to weakly foliated, consisting to bluish-green to yellowish-green to sheaf-like aggregate of hornblende set in a fine grain matrix of tabular plagioclase. A total of 25 water samples, obtained from...
Integrated sedimentological and geochemical studies have been carried out on the sediments of the Lokoja and Patti Formations within the southern Bida Basin with a view to deducing the provenance, palaeodepositional characteristics and tectonic history of the sediments. Field observations show that the Lokoja Formation is made up of conglomerates, coarse to medium grained sandstone and claystone while the Patti Formation consists of medium – fine grained sandstone, claystone, shale, siltsto...
ABSTRACT The challenge of accomplishing C-C bond formation while protecting sensitive functional groups and overcoming problems of stereo-control has led to the use of transition-metal organometallic compounds in organic compounds synthesis. Nucleophilic additions to cationic dienyliron carbonyl complexes provide a convenient means of C-C bond formation. It is highly regioselective and stereospecific making it useful for the synthesis of natural products and compounds with biological activiti...
ABSTRACT The use of chemical fertilizers to replenish depleted soil nutrients due to over cultivation and erosion is a common practice. Natural radionuclides in these fertilizers can cause some radiological adverse health effects to animal, through indirect ingestion of fertilizer, including consumption of plants grown with fertilizers. Information on the level of contribution of chemical fertilizers to farm soil radioactivity and radiological health effects in Nigeria are scanty. This study ...
Abstract Background: The emergence of Anopheles populations capable of withstanding lethal doses of insecticides has weakened the efficacy of most insecticide based strategies of vector control and, has highlighted the need for further studies on the mechanisms of insecticide resistance and the various factors selecting resistant populations of mosquitoes. This research targeted the analysis of breeding sites and the oviposition behaviour of susceptible and resistant populations of Anopheles ...
ABSTRACT Traffic-related emissions contribute immensely to ambient air pollution in urban areas and Traffic Wardens (TW) have been reported to be at high risk of respiratory problems. Although data on road traffic emissions are available in Nigeria, information on personal exposure of traffic wardens to particulate matter is lacking. This study was designed to characterize traffic emissions and compare lung function status of TW with Regular Policemen (RP) in two Local Government Areas (LGA) ...
Abstract: Problem statement: Urinary schistosomiasis is highly endemic in Nigeria and for effective control measure, an efficient, quick and yet cheap diagnosis should be integrated. This will ensure the proper management of infection due to Schistosoma haematobium in low resource communities of Nigeria. Approach: This cross-sectional study recruited a total of 456 (252 males, 204 females) school children aged 3-20 years between November 2010 and June 2011. Urine samples were examined macrosc...
ABSTRACT Pneumatic Transfer System (PTS) is an auxiliary system of Ghana Research Reactor -1 (GHARR-1) to transfer sample capsule in and out of the reactor irradiation sites. The PTS controller unit design and construction was carried out because the transfer system was not designed to operate in cyclic Neutron Activation Analysis (NAA) and as a result could not determine radionuclides whose half-lives are equal or less than 100 seconds. In addition, most of the components used to design th...
ABSTRACT The use of medicinal plants has been found to be effective in the treatment of diseases such as cancer. Aframomum longiscapum seed has been used in the treatment of cancer in ethno medicine but has not been subjected to appropriate scientific evaluation. This study was therefore designed to evaluate the protective effect of Aqueous Extract of Aframomum longiscapum (AEAL) seed against sodium arseniteand ethanol-induced hepatotoxicity and clastogenicity in male Wistar rats. Phytochemic...
ABSTRACT Cocoa beans at the Toma Warehouses were found to be contaw minated with a tota l number o f 21 fungus sp ecies, the predominant species belonging to the genus A spergillus. The annual average contamination was 4,9 per centi Infection in the main crop was lower (3»9 per cent) than in the minor crop (6 ,4 per ce n t). The higher the bean moisture content the greater the fungal in fe ctio n . Extracts o f testa of fermenting cocoa beans depressed vegetative growth in Aspergillu s f la ...
Scientific efforts in the eradication of neglected tropical diseases, such as those caused by the parasitic helminthes, can be improved if a database of key virulence factors directly implicated in pathogenesis is available. As a first step towards creating SchistoVir, a database of virulence protein factors in schistosomes, in this study, we curated, annotated and aligned sequences of twenty virulence factors identified from the literature, using several bioinformatics tools including UniPro...
ABSTRACT This paper presents the relationship between thermo f7hysical properties (thermal conductivity and thermal diffusivity) and heavy metal concentration of some surface clay from six local governments in Ibaaun, oyo state, Nigeria. An atomic absorption spectrometer (AAS) 1i1i)as used in analping the concentration of heavy metals present in each sample by .measuring the intensity of external radiation absorbed by the atom produced from the same sample at a wavelength characteristic to th...
ABSTRACT: Stored dried cassava chips are known to become heavily damaged by Prostephanus truncatus (Hum). A laboratory study was undertaken to determine the extent of losses that this insect pest could cause on TME 30572, the mean weight loss (±SD) rose to 36.93 ± 24.43'% over the period of 112 days compared with 63.2 ± 3.37% for TME I, under the same period and experimental condition, At each time interval of 28 days during which the cassava dried chips were examined, the weight loss in ...