ABSTRACT Glutathione and enzymes such as glutathione S-transferase (GST), glutathione reductase (GR) and superoxide dismutase (SOD) play crucial roles in defending the cell against reactive oxygen species (ROS) which have been implicated in HIV replication. It has been shown that cells infected with HIV generate large amounts of inflammatory products such as superoxide anions, peroxynitrites and other ROS, and is accompanied by the deregulation of antioxidant enzymes. The pro-oxidative stress...
ABSTRACT Comparative studies have been done on the dynamics and management of the fish populations in Abrubi lagoon (closed lagoon) and Densu delta (open lagoon) in Ghana from May 1994 to April 1996.Some environmental parameters of the lagoons, which affected fish populaations were also monitored. There was a noticeable increase in temperature during the dry season (November to March) in both study areas. Temperatures ranged from 26°C to 33°C. On the whole, changes in pH were gradual and st...
Abstract This thesis presents a detailed description and analysis of Bregman’s iterative method for convex programming with linear constraints. Row and block action methods for large scale problems are adopted for convex feasibility problems. This motivates Bregman type methods for optimization. A new simultaneous version of the Bregman’s method for the optimization of Bregman function subject to linear constraints is presented and an extension of the method and its application to solving...
ABSTRACT The Dahomeyide suture zone marks continental amalgamation between the Paleoproterozoic West African Craton (WAC) and the Sahara Metacraton (SMC). This suture zone of the PanAfrican orogenic belt is encrusted by UHP/HP metamorphic rock bodies and associated ultramafic igneous plutonic rocks in SE Ghana through to Togo and Benin. The main identified rock types consist of mafic granulites (hornblende-garnet-pyroxene gneiss and pyroxenegarnet-hornblende gneiss), felsic gneiss, eclogite a...
ABSTRACT V Yeast mating type locus gene alpha2 (MATa2), Yeast G protein complementing gene ( YGC1) and minichromosome maintenance gene (M C M 1) have been identified by isolation of plasmids that are able to complement or suppress a gpa1::HIS3 mutation. MATa2 and YGC1 rescue both MATa and M A Ta-gpa1::HIS3 haploid cell types whereas MCM1 complements only MATa gpal::HIS3 cell type. MATa2 is known to be a general repressor and a determinant of both haploid and diploid cell types. MCM1 is known ...
Abstract Background: Mycobacterium africanum (MAF) and Mycobacterium tuberculosis sensu strico (MTBss) are two members of a closely related bacterial species of Mycobacterium tuberculosis complex (MTBC) that causes tuberculosis (TB) in humans. However MAF is known to cause up to 50% of human pulmonary TB in West Africa only. MAF has been subdivided into MAF West African 1 (MAF1) (Lineage 5) and MAF West African 2 (MAF2) (Lineage 6), as two distinct phylogenetical lineages within MTBC. Subsequ...
Most experimental situations call for standard designs that can be constructed with many statistical software packages. In some situations, however, standard designs are not appropriate or practicable. Computer-aided designs are experimental designs that are generated based on a particular optimality criterion and are generally optimal only for a specified model. In this work designs are generated for non-standard multifactor experiment using D-optimality criterion. The experiment invo...
Several non-linear models have been proposed by various authors for the analysis of growth data. In this thesis, three models, viz, Gompertz, Exponential and Polynomial models were used to analyze some forestry data, namely, a tree species known as Tectona Grandis, collected in the Guinea savanna zone of Nigeria. The three models were compared and using the criteria of low mean square error and high coefficient of determination, it was found that the Gompertz model fits the data best, e...
Complexes of 4 - Cyanobenzaldehydecylohexyl acetic acid hydrazone ( 4-CBAH) with M(II) sulphates and acetates have been synthesized (M=Ni, Cu, Co and Zn). The complexes were characterized by elemental analyses, conductance, infrared and electronic spectral studies. The sulphate ions are in the outer coordination sphere, so also the acetate 10ns. The electronic spectral studies of the isolated complexes indicate an octahedral coordination for Ni 2 + and Co 2 + complexes while Cu 2 +...
Quaternary ammonium compound was synthesized from epoxy and fatty amine reaction. Fourier Transform Infrared(FTIR) spectrometric analysis of the starting materials, and the final product(N-benzyl-N,N-dioctyl-2-hydroxy-3 phenoxypropylammonium chloride) were conducted, and results showed a disappearance of sharp N-H peak of 2oamine, and appearance of broad O-H peak of alcohol in the spectrum of the final product. Mass spectrometric(MS)analysis of the final product was also conducted, and ...
The world as we know it today, continues to rapidly evolve with the impact of the digital age across various sectors (educational, personal, business, social, professional etc.) as we navigate through our daily interactions in the new age. One of such remarkable impact of technology in this new millennium is the progressive growth in the educational sector spurred by the integration of Information and Communications Technology (Apena, 2012). Thus, within this period, ICT is considered am...
ABSTRACT The use of beam modifiers in today’s radiotherapy is very important as it attenuates the beam and reduces the dose to the patient; therefore the need to know the amount of attenuation (in terms of a transmission factor) they provide during treatment. The purpose of this research work is to evaluate the variation (or dependence) of the transmission factors (TFs) of block tray and physical wedges (of different angles) as a function of treatment depth and field size using both iso-cen...
ABSTRACT The limited ability of molecular typing methods to differentiate Mycobacterium ulcerans strains from the same geographic areas, particularly at the local level, hampers our understanding of Buruli ulcer (BU) epidemiology and calls for the search for molecular epidemiological tools with higher discriminatory power. Moreover, the current available laboratory tests for BU diagnosis have various limitations, ranging from low diagnostic sensitivities to financial and technical constraints...
This dissertation presents a systematic and critical study of the fundamenta.lli of soft set theory which includes soft set operations, soft set relations and functions, soft matrices and their properties. In course of studying operations on soft sets, the complementation operation is strengthened, some new results on distributive and absorption properties with respect to various soft set operations are obtained,and soft set operations and their corresponding soft matrix operations are s...
Yersinia enterocolitica and Yersinia pseudotuberculosis are important food and water borne pathogens that has recently emerged world wide. This study was aimed at characterizing the prevalence of Yersinia enterocolitica and Yersinia pseudotuberculosis in human and selected animal populations in Jos and its environment. Three thousand stool samples from human and selected animal species from 5 different locations in Jos and its environs were surveyed over a period of three years. Human s...